Publications by authors named "Pei-Shyuan Lee"

Background: Varicose veins (VV) and mitral valve regurgitation (MR) are both common diseases. The aim was to investigate whether VV are associated with an increased risk of MR.

Methods: We conducted a nationwide cohort study to assess the association between VV and risk of developing MR.

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Article Synopsis
  • The study aimed to identify significant genetic associations by comparing genetic information of varicose vein patients with healthy individuals.
  • The research involved collecting clinical and demographic data from patients and analyzing their genetic samples against a database of sex-matched healthy controls.
  • The results revealed six significant single nucleotide polymorphisms (SNPs) linked to different genes, suggesting potential areas for further investigation in understanding varicose veins.
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The effects of genetic variants on the interaction between hyperlipidemia and sex have not been investigated among gout patients in Taiwan. Using Taiwan Biobank and the National Health Insurance Research Database (NHIRD), we examined hyperlipidemia, sex, and their relationship with gout among Taiwanese adults with the human leukocyte antigen B (HLA-B) genetic variants. Hyperlipidemia was present in 1437 patients with gout.

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