Synchrotron radiation (SR) diffraction enhanced imaging (DEI) of chronic glomerulonephritis (CGN) mode.

Objective: The aim of this study is to investigate microstructural changes in chronic glomerulonephritis (CGN) rabbit model under diffraction enhanced imaging (DEI) technology of synchrotron radiation (SR).

Materials And Methods: The chronic glomerulonephritis (CGN) models were obtained within two months after 5 New Zealand white rabbits were treated with doxorubicin hydrochloride. Blood exams, urine tests and kidney histological studies were carried out after the 5 rabbits were humanely sacrificed by hyperanesthesia.

Visualising liver fibrosis by phase-contrast X-ray imaging in common bile duct ligated mice.

Objectives: To determine whether phase-contrast X-ray imaging can be used to visualise directly the accumulated extracellular matrix proteins associated with liver fibrosis in common bile duct ligated mice.

Methods: Twenty-six-week-old C57BL female mice were randomised into three groups. In groups 1 (n = 5) and 2 (n = 10), common bile duct ligation was conducted to produce secondary biliary cirrhosis.

[Application research of DEI technique based on synchrotron X-ray source in imaging rabbit eyeball in vitro].

Objective: To study the application of DEI technique in imaging the small structures of rabbit eyeball.

Method: DEI technique was used to image the eyeball of New Zealand white rabbit in vitro. The experiments were performed using beamline 4W1A at the topography station of Beijing Synchrotron Radiation Facility (BSRF).

Mouse blood vessel imaging by in-line x-ray phase-contrast imaging.

It is virtually impossible to observe blood vessels by conventional x-ray imaging techniques without using contrast agents. In addition, such x-ray systems are typically incapable of detecting vessels with diameters less than 200 microm. Here we show that vessels as small as 30 microm could be detected using in-line phase-contrast x-ray imaging without the use of contrast agents.

Strategy of extraction methods and reconstruction algorithms in computed tomography of diffraction enhanced imaging.

Computed tomography of diffraction enhanced imaging (DEI-CT) is a novel x-ray phase-contrast computed tomography which is applied to inspect weakly absorbing low-Z samples. Refraction-angle images which are extracted from a series of raw DEI images measured in different positions of the rocking curve of the analyser can be regarded as projections of DEI-CT. Based on them, the distribution of refractive index decrement in the sample can be reconstructed according to the principles of CT.