Syntheses, Structural Analyses, and Properties of Condensed Arenes with Multihelicity.

A -symmetric hexapole helicene (HH) and a -symmetric dodecapole helicene (DH) were prepared, and their three-dimensional structures were verified by X-ray crystallography and density functional theory calculations. The molecular geometries and local helical configurations of their most stable diastereomers were correctly predicted by arranging suitable conformations of the peripheral aryl rings. Importantly, the outermost three [5]helicenes with a consistent configuration in DH were observed to increase the thermostability, enantiomerization barrier (Δ = 40.

2,3 : 6,7-Naphthalene Bis(dicarboximide) Cyclophane: A Photofunctional Host for Ambient Delayed Fluorescence in Solution.

Harvesting triplet excitons of heavy atom-free purely organic chromophores under aerated conditions is challenging due to the quenching of long-lived triplet states by molecular oxygen and vibrational dissipation. Herein, we show a supramolecular approach of triplet harvesting via mitigating quenching pathways of a triplet harvester. Specifically, we used a host-guest system based on 2,3 : 6,7-naphthalene bis(dicarboximide)-derived cyclophane (NBICy) and carbazole derivative (EtCz).

Cellular mechanism underlying leptin-induced anion secretion of rat epididymal epithelial cells.

Background: A large number of studies have shown that leptin plays an important role in the regulation of fertility via the hypothalamus-pituitary-gonad axis. However, its peripheral function in epididymis was still elusive.

Objective: The purpose of this study was to determine the pro-secretion effect of leptin on the rat epididymal epithelium.

Aerobic exercises regulate the epididymal anion homeostasis of high-fat diet-induced obese rats through TRPA1-mediated Cl- and HCO3- secretion†.

Aerobic exercises could improve the sperm motility of obese individuals. However, the underlying mechanism has not been fully elucidated, especially the possible involvement of the epididymis in which sperm acquire their fertilizing capacity. This study aims to investigate the benefit effect of aerobic exercises on the epididymal luminal milieu of obese rats.

Mechanosensitive Piezo1 channel in rat epididymal epithelial cells promotes transepithelial K secretion.

The Piezo1 channel, a mechanosensitive channel that exhibit a preference for Ca, play multifarious physiological and pathological roles in the endothelium and epithelium of various tissues. However, the functional expression of Piezo1 channel in the epithelium of the male reproductive tract remains unknown. In the present study, the expression of Piezo1 channel in the rat epididymis was determined by real-time quantitative PCR, western blot and immunohistochemical analysis.

Activation of TRPV4 stimulates transepithelial K+ secretion in rat epididymal epithelium.

The maturation of sperms is dependent on the coordinated interactions between sperm and the unique epididymal luminal milieu, which is characterized by high K+ content. This study investigated the involvement of transient receptor potential vanilloid 4 (TRPV4) in the K+ secretion of epididymal epithelium. The expression level and cellular localization of TRPV4 and Ca2+-activated K+ channels (KCa) were analyzed via RT-PCR, real-time quantitative PCR, western blot and immunofluorescence.

[Assessment of enhancement release of Oncorhynchus keta in Suifen River, Northeast China].

To evaluate the effects of enhancement release of Chum salmon (Oncorhynchus keta) in Suifen River, the homing Chum salmon was monitored in Dongning section of Suifen River from 2012 to 2017. A total of 462 samples were collected, 41 samples out of which were tagged indivi-duals which were cut off adipose fin before they were released. The recapture rate and the effects of Chum salmon enhancement release were analyzed and evaluated based on the releasing information.

Influence of the three-dimensional printing technique and printing layer thickness on model accuracy.

Objective: The accuracies of three-dimensional (3D) printed dental models using various digital light processing (DLP) and stereolithography (SLA) printers at different thicknesses were compared.

Materials And Methods: Based on digital dental models (originally digitized using R700; 3Shape, Copenhagen, Denmark), physical dental models were printed using three types of DLP printers: (1) EvoDent (UnionTec, Shanghai, China) with layer thicknesses of 50 μm and 100 μm; (2) EncaDent (Encashape, WuXi, China) with layer thicknesses of 20, 30, 50 and 100 μm; (3) Vida HD (Envisioned, Dearborn, MI, USA) with layer thicknesses of 50 and 100 μm. Models with the SLA printer Form 2 (Formlabs, Somerville, MA, USA) were printed with layer thicknesses of 25, 50 and 100 μm.

[Tongjingling reduces ROS level and improves mitochondrial function in spermatogenic cells of varicocele rats with liver-qi stagnation].

Objective: To explore the effects of the Chinese herbal compound Tongjingling (TJL) on the ROS level, mitochondrial membrane potential (MMP) and mitochondrial ultrastructure in spermatogenic cells in varicocele (VC) rats with liver-qi stagnation (LQS).

Methods: Totally, 72 male SPF Wistar rats were randomly divided into six groups of equal number, sham operation, VC+LQS model, low-, medium- and high-dose TJL, and L-carnitine (LC) control. The VC+LQS model was established by the Saypol method combined with tail-clamping.

[Soft tissue angle evaluation of fixed Twin-Block appliance treatment and tooth extraction treatment in skeletal Class II malocclusion].

Purpose: This cephalometric study was designed to evaluate the soft tissue profile effects of Twin-Block combined with straight wire appliances in the treatment of skeletal Class II malocclusion with mandibular retrognathia in growing individuals by angulation.

Methods: The sample comprised 31 growing individuals with skeletal Class II and mandibular retrognathia, which were divided into 2 groups. One group (18 patients) was treated with fixed Twin-Block combined with fixed appliance， the other group (13 patients) was only treated with fixed appliance after tooth extraction.

[Exogenous Sr2+ sedimentation on otolith of chum salmon embryos].

To explore the exogenous Sr2+ sedimentation on otolith of chum salmon embryos, chum salmon embryos were exposed to culture water contained Sr2+ at Sr2+ concentration of 50, 100, 200 or 400 mg . L-1 for 48 h to imitate Sr2+ sedimentation. After a culturing period of 12 d and 100 d, the otoliths of the chum salmon were taken to detect exogenous Sr2+ sedimentation with electro-probe microanalyzer (EPMA).

[Soft tissue linear evaluation of fixed Twin-block appliance treatment and tooth extraction in skeletal Class II malocclusion].

Purpose: This cephalometric study was designed to evaluate the soft tissue profile effects of Twin-block combined with straight wire appliances to treat growing adolescents with skeletal Class II malocclusion and mandibular retrognathia.

Methods: The samples comprised 31 growing individuals with skeletal Class II and mandibular retrognathia. They were divided into 2 groups.

[Efficacy evaluation of fixed Twin-block appliance and tooth extraction in skeletal Class II malocclusion].

Purpose: To evaluate the skeletal and dentoalveolar effects of Twin-Block combined with straight wire appliances and tooth extraction in the treatment of skeletal Class II malocclusion with mandibular retrognathia in growing individuals.

Methods: The sample comprised 31 growing individuals with skeletal Class II and mandibular retrognathia, divided into 2 groups. One group (18 patients) was treated with fixed Twin-block combined with fixed appliance; the other group (13 patients) was only treated with fixed appliance after tooth extraction.