Publications by authors named "Pei-Long Li"

Background: Prenatal ultrasound plays a crucial role in the diagnosis and classification of right aortic arch (AO) with mirror-image branching (RAA-MB). The recent research in this area has primarily focused on qualitative diagnosis, neglecting the quantitative analysis of ultrasound factors that impact RAA-MB outcomes. This study used echocardiography to measure prenatal ultrasound parameters for vascular ring and trachea in fetuses with RAA-MB, employing a nomogram model to evaluate factors influencing their prognosis, thereby providing a comprehensive characterization of potential outcomes.

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Background: Traumatic brain injury (TBI) is a significant cause of morbidity and mortality in pediatric patients, leading to long-term physical, cognitive, and psychological impairments. Blood lactate and fibrinogen levels have emerged as potential biomarkers associated with tissue hypoperfusion and coagulation dysfunction, respectively. However, limited research has specifically focused on the significance of these biomarkers in pediatric TBI.

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Article Synopsis
  • The study investigates the effectiveness of using two-dimensional (2D) and high-definition live (HDlive) flow imaging alongside spatiotemporal image correlation (STIC) for diagnosing total anomalous pulmonary venous connection (TAPVC) in fetuses.
  • Seventeen cases of fetal TAPVC were analyzed, revealing that the combined imaging techniques successfully identified various forms of the condition, including supracardiac and cardiac types.
  • Key indicators for TAPVC diagnosis included a small left atrium, absence of pulmonary vein drainage into the left atrium, and increased distance between the left atrium and descending aorta, highlighting the clinical significance of these imaging methods.
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Preoperative prediction of lymph node (LN) metastasis is accepted as a crucial independent risk factor for treatment decision-making for esophageal squamous cell carcinoma (ESCC) patients. Our study aimed to establish a non-invasive nomogram to identify LN metastasis preoperatively in ESCC patients. Construction of the nomogram involved three sequential phases with independent patient cohorts.

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Background: Foetal vein of Galen aneurysmal malformation (VGAM) is a very rare congenital malformation of the cerebral blood vessels. We sought to evaluate the diagnostic value of ultrasound in combination with magnetic resonance imaging (MRI) in foetal VGAM.

Case Presentation: Prenatal ultrasound combined with MRI diagnosed five cases of VGAM.

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We report on the fabrication of a NO gas sensor from room-temperature reduction of graphene oxide(GO) via two-beam-laser interference (TBLI). The method of TBLI gives the distribution of periodic dissociation energies for oxygen functional groups, which are capable to reduce the graphene oxide to hierarchical graphene nanostructures, which holds great promise for gaseous molecular adsorption. The fabricated reduced graphene oxide(RGO) sensor enhanced sensing response in NO and accelerated response/recovery rates.

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One major reason for the failure of advanced colorectal cancer (CRC) treatment is the occurrence of chemoresistance to fluoropyrimidine (FU)-based chemotherapy. Various reports showed that ectopic expression and function of microRNAs (miRNAs) played key roles to mediate apoptosis at the post-transcriptional level. To further explore the possible mechanisms, we evaluated the prognostic effect of miR-218 in patients with CRC receiving 5-FU-based treatment and investigated the proapoptotic role of miR-218 in vitro.

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Background: Elevated serum sialic acid (SA) and hydroxyproline (Hyp) concentrations have been found in a variety of malignant cancers. We simultaneously detect serum concentrations of SA and Hyp (SA&Hyp) in ovarian cancer, and compare its diagnostic value with classic tumor markers-human epididymis protein 4 (HE4) and carbohydrate antigen 125 (CA125).

Methods: Serum concentrations of SA&Hyp, HE4 and CA125A were detected in a total of 767 serum samples collected from 484 patients with gynecologic diseases, 180 healthy individuals, 45 pregnant women and 58 patients with renal failure using chemical colorimetry and electrochemiluminescence immunoassay (ECLIA), respectively.

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Objective: To analyze the HIV/AIDS epidemics situation among migrant population.

Methods: Data on HIV/AIDS cases among mobile population through case reporting system was collected from 2008 to 2011.

Results: The number of reported cases on HIV/AIDS among mobile population had been rising, with proportions of the total reported cases increased from 10.

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Objective: To study the epidemiological characteristics on the clustering nature of pandemic (H1N1) 2009 in China.

Methods: Time and place distribution of pandemic (H1N1) 2009 on the nature of clustering through data from Public Health Emergency Management Information System were described.

Results: As of August 10, 2010, 2773 pandemic (H1N1) 2009 clusters, a total of 77 363 cases (including 20 deaths) were reported in the mainland of China.

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Objective: To analyze the HIV/AIDS epidemic situation and related behavioral components among young students in the last years and to provide information for integrated control and prevention programs.

Methods: Data on young students (15 - 24 years) through case reporting system was collected from 2006 to 2009 and continuous sentinel surveillance data regarding 6 national sentinel sites carried out from 2006 to 2009 was also collected. The sentinel sites would include universities, junior college and secondary vocational colleges registered students, using cluster sampling phases method.

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Objective: To sequence and analyze the complete genome of two new Japanese encephalitis virus (JEV) strains isolated from mosquitoes collected in Hubei province in 2008, and to understand the molecular biological characteristics of JEV in this area.

Methods: RT-PCR was used to amplify the fragments of HBZG08-09 strain and HBZG08-55 strain with 16 pairs overlapping primers after they had been recovered and identified, then the full-length genome was obtained by sequencing and splicing. Biological sequence alignment, nucleotide and amino acid sequence analysis, phylogenetic analysis and analysis of amino acid differences were performed by the software of Clustal X (1.

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Article Synopsis
  • The study analyzed mosquito characteristics and major mosquito-borne diseases like epidemic encephalitis B and malaria in the Three Gorges Reservoir Area from 1997 to 2008.
  • Data was collected through health surveillance and meteorological information, utilizing Pearson and Poisson models to identify trends.
  • Results indicated a decrease in disease incidence, a positive correlation between mosquito density and temperature, and a need for ongoing surveillance to assess long-term impacts following the construction of the Three Gorges Reservoir.
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Article Synopsis
  • * Key findings showed that major causes of death included circulatory system and respiratory diseases, accounting for nearly 91% of all deaths, while water-borne and zoonosis diseases remained relatively low.
  • * Overall, environmental changes from sluicing didn't significantly affect health, but increased monitoring of disease vectors is advised for better disease transmission control.
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