[Marine Emission Inventory and Its Temporal and Spatial Characteristics in the City of Shenzhen].

To analyze the characteristic of marine emission in Shenzhen City, activity-based and fuel-based approaches were utilized to develop the marine emission inventory for the year of 2010, using the vessel files from the Lloyd's register of shipping (LR) and vessel track data from the automatic identification system (AIS). The marine emission inventory was temporally (resolution: 1 hour) and spatially (resolution: 1 km x 1 km) allocated based on the vessel track data. Results showed that total emissions of SO2, NO(x), CO, PM10, PM2.

Characteristics of respiratory syncytial virus-induced bronchiolitis co-infection with Mycoplasma pneumoniae and add-on therapy with montelukast.

Background: The influence of Mycoplasma pneumoniae (MP) infection on bronchiolitis remains unclear. Additionally, reports on the efficacies of leukotriene receptor antagonists in the treatment of bronchiolitis have been inconclusive.

Methods: Children with respiratory syncytial virus (RSV)-induced bronchiolitis were divided into two groups: RSV+MP group and RSV group.

Add-on therapy with montelukast in the treatment of Henoch-Schönlein purpura.

Background: Previous studies suggested that leukotrienes (LT) were involved in the pathogenesis of Henoch-Schönlein purpura (HSP). This study investigated the efficacy of an add-on therapy with montelukast in the treatment of HSP.

Methods: In this four-center, double-blind, placebo-controlled, parallel paired comparative study, 130 children with HSP were divided into two large groups: 84 patients without nephritis and 46 patients with nephritis.

[Reversed changes of the 15-lipoxygenase product lipoxin A₄ and the 5-lipoxygenase product leukotriene C₄ in children with asthma].

Objective: To investigate the expressions of 15- and 5-lipoxygenases in leukocytes and the changes of the levels of blood lipoxin A₄ (LXA₄) and leukotriene C₄ (LTC₄) in children with asthma.

Methods: The mRNA levels of 15- and 5-lipoxygenases in leukocytes were assessed by RT-PCR, and the levels of blood LXA₄ and LTC₄ were determined by ELISA, in 106 children with mild, moderate and severe asthma. Forty healthy children served as the controls.

Reversed changes of lipoxin A4 and leukotrienes in children with asthma in different severity degree.

Objectives: To investigate the expressions of 15-lipoxygenase (15-LO) and 5-lipoxygenase (5-LO) in leukocytes and the changes of blood lipoxin A(4)(LXA(4)), leukotriene (LT)B(4) and LTC(4) in children with asthma, and to explore the relationship between the blood eicosanoids and one of serum high-sensitivity C-reactive protein (hsCRP), interleukin (IL)-5, IL-8 and IL-13 and IgE in children with asthma.

Study Design: One hundred six asthmatic children were divided into three groups, that is, mild persistent asthmatic group, moderate persistent asthmatic group and severe persistent asthmatic group. Forty healthy children were served as controls.

Inverse temporal changes of lipoxin A4 and leukotrienes in children with Henoch-Schönlein purpura.

The pathogenesis of Henoch-Schönlein purpura (HSP) is not clearly understood. It remains unclear how changes of lipoxin A(4) (LXA(4)) that acts as a "braking signal" in inflammatory process occur in patients with HSP. In this study, we determined the temporal changes of blood and urinary LXA(4), Leukotriene (LT)B(4) and urinary LTE(4) in 49 children with HSP.

Elevated expressions of 15-lipoxygenase and lipoxin A4 in children with acute poststreptococcal glomerulonephritis.

Anti-inflammatory effects of the 15-lipoxygenase (15-LO) derivatives lipoxin A(4) (LXA(4)) and 15-S-hydroxyeicosatetraenoic acid (15-S-HETE) have been documented in many experimental models of acute inflammation. However, the expression levels of 15-LO and its products in human renal diseases remain unknown. This study investigated the expression levels of LXA(4), leukotriene B(4) (LTB(4)), and 15-LO in leukocytes and glomeruli obtained from 22 children with acute poststreptococcal glomerulonephritis (APSGN), and determined the modulatory effects of both 15-S-HETE and LXA(4) on LTB(4) synthesis in leukocytes and LTB(4)-evoked chemotaxis of polymorphonuclear leukocytes (PMNs) obtained from children during the first 3 days after onset of APSGN.