Publications by authors named "Pei-Kun Xu"
Article Synopsis
- * Data from 31 patients show that this technique successfully guided punctures and accurately displayed intracranial targets, confirming effectiveness through postoperative imaging and results.
- * The findings suggest that this method is safe, simple to use, and beneficial for precise diagnosis and treatment in neurosurgery, indicating its potential for wider application.
Objective: The cystic gliomas are the special type of malignant tumors in the brain and often lead to unsatisfied prognosis, but the microsurgical resection is still the most important treatment. However, they are difficult to be totally removed with craniotomy, especially for those who have flimsy cyst walls. Recently, we attempted to resect them via an innovative surgical technique, "Gelfoam Padding", in order to improve the total resection rate of the tumors safely.
View Article and Find Full Text PDFBackground: Our previous studies have shown that mesencephalic astrocyte-derived neurotrophic factor (MANF) provides a neuroprotective effect against ischemia/reperfusion injury and is also involved in inflammatory disease models. This study investigates the potential role and mechanism of MANF in acute brain damage after traumatic brain injury (TBI).
Methods: The model of TBI was induced by Feeney free falling methods with male Sprague-Dawley rats.