Publications by authors named "Pei-Jie Lu"
Article Synopsis
- - The study explores the potential of using CRISPR/Cas9 and induced pluripotent stem cells (iPSCs) as a treatment for Charcot-Marie-Tooth disease (CMT), a neurological condition that currently has no effective clinical treatment.
- - Researchers reprogrammed skin fibroblasts from CMT type 2D patients to create iPSCs and successfully repaired a specific genetic mutation responsible for the disease using CRISPR/Cas9 technology.
- - The successful generation of genetically corrected iPSCs lays the groundwork for future treatments, suggesting a promising direction for developing autologous cell therapies for degenerative neurological diseases like CMT.
