Publications by authors named "Pei-I Su"
Article Synopsis
- Extracorporeal cardiopulmonary resuscitation (ECPR) can help improve outcomes for patients experiencing in-hospital cardiac arrest (IHCA), and the RESCUE-IHCA score was created to predict the outcomes of these patients.
- A study involving 324 ECPR-treated IHCA patients showed that the RESCUE-IHCA score maintained similar performance in predicting mortality compared to the original cohort, with key findings indicating that longer cardiac arrest duration increases mortality risk while certain initial heart rhythms lower that risk.
- Unlike the original study, factors like age, the timing of resuscitation, disease category, and pre-existing renal issues did not significantly correlate with in-hospital death in this Asian medical center's
Article Synopsis
- The study aimed to validate and compare statistical and machine learning models for predicting outcomes after out-of-hospital cardiac arrest, while also assessing the impact of COVID-19 on these predictions.
- The analysis included 2,161 adult patients from 3 hospitals between 2015 and 2023, focusing on neurological outcomes at hospital discharge and comparing performance before and after 2020.
- The Utstein-Based Return of Spontaneous Circulation score showed the best predictive performance (AUC 0.85), significantly outperforming other models, particularly after the onset of the COVID-19 pandemic.
Background: Using deep learning for disease outcome prediction is an approach that has made large advances in recent years. Notwithstanding its excellent performance, clinicians are also interested in learning how input affects prediction. Clinical validation of explainable deep learning models is also as yet unexplored.
View Article and Find Full Text PDFBackground: This study aimed to investigate the association between the temporal transitions in heart rhythms during cardiopulmonary resuscitation (CPR) and outcomes after out-of-hospital cardiac arrest.
Methods: This was an analysis of the prospectively collected databases in 3 academic hospitals in northern and central Taiwan. Adult patients with out-of-hospital cardiac arrest transported by emergency medical service between 2015 and 2022 were included.
Article Synopsis
- ! Current guidelines for extracorporeal cardiopulmonary resuscitation (ECPR) highlight the need for careful patient selection, but lack specific criteria; this study investigates the role of arterial carbon dioxide tension (PaCO) during CPR in predicting neurological outcomes for out-of-hospital cardiac arrest (OHCA) patients receiving ECPR. * ! The study analyzed 152 OHCA patients from 2012 to 2020, finding that PaCO was independently associated with favorable neurological outcomes, particularly identifying a cutoff of PaCO < 70 mmHg as predictive of improved outcomes. * ! The results suggest that measuring PaCO can help determine which OHCA patients are good candidates for ECPR, even those with less favorable conditions
Background: The 2022 AHA/ACC/HFSA guidelines for the management of heart failure (HF) makes therapeutic recommendations based on HF status. We investigated whether the prognosis of in-hospital cardiac arrest (IHCA) could be stratified by HF stage and left ventricular ejection fraction (LVEF).
Methods: This single-center retrospective study analyzed the data of patients who experienced IHCA between 2005 and 2020.
Article Synopsis
- The RACA score is a model used to predict the likelihood of "return of spontaneous circulation" (ROSC) in patients who experience out-of-hospital cardiac arrest (OHCA), incorporating factors such as age, gender, arrest cause, and more.
- The study aimed to enhance the RACA score by including end-tidal carbon dioxide (EtCO) measurements during CPR, creating the EtCO + RACA score to better estimate ROSC for patients taken to the emergency department.
- Data from 530 patients were analyzed, finding that the EtCO + RACA score showed strong predictive ability for ROSC, demonstrating better performance compared to the traditional RACA score.
Introduction: Following cardiac arrest, return of spontaneous circulation (ROSC) in patients may be followed by spontaneous neurological recovery, which may decrease the potential adverse effects of treatments in post-cardiac arrest care, including those of Targeted Temperature Management (TTM). We investigated the percentage of post-arrest patients who experienced spontaneous neurological recovery, and the characteristics and neurological outcomes of these patients.
Methods: A total of 540 patients with ROSC were retrospectively enrolled in this single-center observational study.
Background: Intra-abdominal adhesions develop after nearly every abdominal surgery, commonly causing female infertility, chronic pelvic pain, and small bowel obstruction. Pentoxifylline (PTX) is a methylxanthine compound with immunomodulatory and antifibrotic properties. The aim of this study was to investigate whether PTX can reduce post-operative intra-abdominal adhesion formation via collagen deposition, tissue plasminogen activator (tPA) level, inflammation, angiogenesis, and fibrosis.
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