Characterization of odor-active compounds in cooked meat of farmed obscure puffer (Takifugu obscurus) using gas chromatography-mass spectrometry-olfactometry.

The volatile and odor-active compounds in cooked meat of farmed obscure puffer (Takifugu obscurus) were analyzed by gas chromatography-mass spectrometry-olfactometry (GC-MS-O). The volatile compounds were extracted by the simultaneous distillation-extraction (SDE) method, then separated and identified by GC-MS. Odor-active compounds in the SDE extract were characterized by GC-MS-O.

microRNA-449a suppresses non-small cell lung cancer.

This study was set to determine the expression of microRNA-449a in cancer tissue and serum of non-small cell lung cancer (NSCLC) patients and explore the underlying mechanisms of its tumor suppressor functions. We selected 50 NSCLC patients in our hospital as the lung cancer group and 50 healthy volunteers as the control group. RT-PCR was performed to detect the expression levels of microRNA-449a in NSCLC tissue and the plasma of NSCLC patients.

Synthesis and antioxidative activity of 2-substituted phenyl-5-(3'-indolyl)-oxazole derivatives.

Aim: To study the synthesis of 5-(3'-indolyl)-oxazoles and their antioxidative activity.

Methods: The amides were prepared from tryptophan and different acid derivatives by the catalytic dehydration of dicyclohexyl carbodiimide (DCC). The characteristic heterocyclic ring system of 5-(3'-indolyl)-oxazoles was constructed by oxidative cyclization of amide, using dicholorodicyanoquinone (DDQ).