Publications by authors named "Pei-Chun Xu"
Objective: We aimed to investigate the association between gastrointestinal ultrasound (GIUS) and capsule endoscopy (CE) in assessing disease activity in patients with small bowel Crohn's disease (CD).
Methods: Medical records of 74 patients with small bowel CD who were treated at our hospital between January 2020 and March 2022 were retrospectively reviewed, including 50 men and 24 women. All patients underwent both GIUS and CE within one week after their admissions.
Article Synopsis
- Ultrasound can help track treatment effectiveness in Crohn's disease (CD), but how it correlates with anti-TNF drug levels hasn't been clear until now.
- The study involved 92 patients receiving anti-TNF therapy, with evaluations of ultrasound responses and drug levels at specific time points.
- Results showed that higher levels of anti-TNF drugs were linked to better ultrasound outcomes, suggesting that monitoring drug levels could improve treatment for CD.
Objectives: Deep remission should be induced early in the disease course of Crohn's disease (CD), because it significantly prevents disease progression. Identifying predictors of deep remission before treatment is important to guide therapeutic strategy. Little is known about the predictors of infliximab-induced deep remission in treatment-naïve patients with isolated small bowel CD.
View Article and Find Full Text PDFObjectives: The efficacy of infliximab in treatment-naïve patients with stricturing small bowel Crohn's disease (CD) has not been well studied. We aimed to evaluate the efficacy of infliximab in these patients.
Materials And Methods: This was a retrospective study of all consecutive treatment-naïve patients with newly diagnosed CD with small bowel stricture who started regular infliximab therapy in Nanfang Hospital between January 2015 and December 2019.