Publications by authors named "Pei-Bin Ma"
Amatoxin poisoning induces delayed-onset acute liver failure, which are responsible for more than 90% of deaths in mushroom poisoning. It has been postulated from animal and human studies that biliary drainage interrupting enterohepatic amatoxin circulation may affect amatoxin poisoning. Dogs were randomly divided into four groups of six animals each.
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- The study evaluated the toxicity of the lethal mushroom A. exitialis and its peptide toxins using beagles, which showed signs of toxicity such as vomiting and diarrhea after ingestion.
- The toxicokinetics showed that specific toxins like α-amanitin and β-amanitin were rapidly absorbed and eliminated from the plasma, with acute liver damage occurring after a 12-24 hour latency period.
- Treatment methods like gastric lavage and hemodialysis were ineffective post-ingestion, but enhanced urinary excretion of amatoxins may be beneficial within the first two days after consumption.
Objective: To evaluate four therapeutic measures on acute tetramethylene disulphotetramine (TETS) poisoning and the effects of it on intelligence of children.
Methods: All 86 patients of acute TETS poisoning were randomly divided into 4 groups (the control group, sodium valproate group, sodium dimercaptopropane sulfonate group and the hemoperfusion group). The therapeutic effects were observed after the arranged treatment was administrated.