Application of lignin and lignin-based composites in different tissue engineering fields.

Lignin is a major phenolic polymer from the plant biomass. Due to its abundant functional groups (carboxyl and hydroxyl groups), lignin could act as an antioxidant, antimicrobial as well as an immune modulator. These remarkable biological properties render lignin a highly potential bioactive candidate in the biomedical applications including tissue engineering.

Research on the Corrosion Behavior of Q235 Pipeline Steel in an Atmospheric Environment through Experiment.

Low-carbon steel pipelines are frequently used as transport pipelines for various media. As the pipeline transport industry continues to develop in extreme directions, such as high efficiency, long life, and large pipe diameters, the issue of pipeline reliability is becoming increasingly prominent. This study selected Q235 steel, a typical material for low-carbon steel pipelines, as the research object.

Zrsr2 Is Essential for the Embryonic Development and Splicing of Minor Introns in RNA and Protein Processing Genes in Zebrafish.

ZRSR2 (zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2) is an essential splicing factor involved in 3' splice-site recognition as a component of both the major and minor spliceosomes that mediate the splicing of U2-type (major) and U12-type (minor) introns, respectively. Studies of -depleted cell lines and -mutated patient samples revealed its essential role in the U12-dependent minor spliceosome. However, the role of during embryonic development is not clear, as its function is compensated for by in mice.

Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy in Young Patients With Peritoneal Metastasis of Colorectal Cancer-An Asian Experience.

Introduction: Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) are accepted treatment options for patients with cancers associated with the abdominal region. Currently, there are insufficient data that evaluate the effectiveness of these therapeutic options in young patients who have peritoneal metastasis (PM) originating from colorectal cancer.

Methods: In this investigation, we evaluated perioperative data, clinicopathological manifestations, and survival consequences in 46 younger (≤50 y) patients who underwent CRS and HIPEC therapy between 2017 June and 2019 June and then compared these data with 94 older patients (aged >50 y).

An automatic fluorescence phenotyping platform to evaluate dynamic infection process of -green fluorescent protein in tobacco leaves.

Tobacco is one of the important economic crops all over the world. (TMV) seriously affects the yield and quality of tobacco leaves. The expression of TMV in tobacco leaves can be analyzed by detecting green fluorescence-related traits after inoculation with the infectious clone of TMV-GFP (Tobacco mosaic virus - green fluorescent protein).

Staring Imaging Attitude Tracking Control Laws for Video Satellites Based on Image Information by Hyperbolic Tangent Fuzzy Sliding Mode Control.

This paper studies the staring imaging attitude tracking and control for satellite videos based on image information. An improved temporal-spatial context learning algorithm is employed to extract the image information. Based on this, a hyperbolic tangent fuzzy sliding mode control law is proposed to achieve the attitude tracking and control.

The preparation technology and application of xylo-oligosaccharide as prebiotics in different fields: A review.

Xylo-oligosaccharide (XOS) is a class of functional oligosaccharides that have been demonstrated with prebiotic activity over several decades. XOS has several advantages relative to other oligosaccharide molecules, such as promoting root development as a plant regulator, a sugar supplement for people, and prebiotics to promote intestinal motility utilization health. Now, the preparation and extraction process of XOS is gradually mature, which can maximize the extraction and avoid waste.

Non-Invasive Stable Sensory Feedback for Closed-Loop Control of Hand Prosthesis.

The absence of somatotopic sensory feedback limits the function of conventional prosthetic hands. In this study, we integrated a non-invasive sensory feedback system into a commercial Bebionic hand with new customized surface stimulation electrodes. Multiple modalities of tactile and hand aperture sensory information were conveyed to the amputee via the technique of evoked tactile sensation (ETS) elicited at projected finger map (PFM) of residual limb and an additional electrotactile stimulation in the ipsilateral upper arm.

Investigating the Relationship Between Overexposure to Ultraviolet Radiation and Rheumatoid Arthritis Using National Health and Nutrition Examination Survey (NHANES) 2015-2016 Data.

Background Research on the association between sunburn and autoimmune diseases including rheumatoid arthritis is scarce. To date, no study has looked at the relationship between over-exposure to ultraviolet (UV) radiation indicated by sunburn and rheumatoid arthritis (RA). We addressed this gap using the United States National Health and Nutrition Examination Survey (NHANES) database following a hypothesis that no relationship exists between sunburn and rheumatoid arthritis.

Thiacalix[4]arene-based complex with Co(II) ions as electrode modifier for simultaneous electrochemical determination of Cd(II), Pb(II), and Cu(II).

A complex [Co(TCTA)(HO)]∙10HO (Co-TCTA) based on thiacalix[4]arene derivative has been synthesized for the first time using the solvothermal method. The glassy carbon electrode (GCE) modified with Co-TCTA (Co-TCTA/GCE) could simultaneously determine Cd, Pb, and Cu at around - 0.75 V, - 0.

Impact of homologous recombination deficiency biomarkers on outcomes in patients with early breast cancer: a systematic review protocol.

Introduction: Patients with breast cancer with homologous recombination deficiency (HRD) such as germline BRCA1/2 mutations would respond to DNA-damaging drugs. Several clinical studies have revealed that HRD biomarkers were associated with the outcomes of patients with early breast cancer (EBC). However, no systematic review has determined the prognostic role of HRD biomarkers in patients with EBC.

Operating interfaces to synthesize L1-FePt@Bi-rich nanoparticles by modifying the heating process.

A facile strategy to operate interfaces when synthesizing L1-FePt@Bi-rich nanoparticles (NPs) has been proposed. Two interfaces are indispensable to obtain the high ordering L1-FePt structure. One is the mismatched interfaces between the initial γ-PtBi nuclei and the disordered fcc-FePt phase.

Lignin-carbohydrate complexes suppress SCA3 neurodegeneration via upregulating proteasomal activities.

Lignin-carbohydrate complexes (LCCs) represent a group of macromolecules with diverse biological functions such as antioxidative properties. Polyglutamine (polyQ) diseases such as spinocerebellar ataxia type 3 (SCA3) comprise a set of neurodegenerative disorders characterized by the formation of polyQ protein aggregates in patient neurons. LCCs have been reported to prevent such protein aggregation.

[Treatment of femoral head replacement in elderly patients with femoral neck fracture complicated with uremia].

Objective: To investigate the treatment method and effect of artificial femoral head replacement for elderly patients with femoral neck fracture complicated with uremia.

Methods: From January 2016 to December 2020, 21 elderly patients with femoral neck fracture complicated with uremia were treated with artificial femoral head replacement. There were 3 males and 18 females, aged 65 to 83 years old with an average of (77.

Minimally Invasive Local-Skull Electrophysiological Modification With Piezoelectric Drill.

The research on non-invasive BCI is nowadays hitting the bottleneck due to the humble quality of scalp EEG signals. Whereas invasive solutions that offer higher signal quality in contrast are suffocated in their spreading because of the potential surgical complication and health risks caused by electrode implantation. Therefore, it puts forward a necessity to explore a scheme that could both collect high-quality EEG signals and guarantee high-level operation safety.

Pedestrian Detection by Exemplar-Guided Contrastive Learning.

Typical methods for pedestrian detection focus on either tackling mutual occlusions between crowded pedestrians, or dealing with the various scales of pedestrians. Detecting pedestrians with substantial appearance diversities such as different pedestrian silhouettes, different viewpoints or different dressing, remains a crucial challenge. Instead of learning each of these diverse pedestrian appearance features individually as most existing methods do, we propose to perform contrastive learning to guide the feature learning in such a way that the semantic distance between pedestrians with different appearances in the learned feature space is minimized to eliminate the appearance diversities, whilst the distance between pedestrians and background is maximized.

Urinary exosomes derived circRNAs as biomarkers for chronic renal fibrosis.

Background: Chronic renal disease (CKD) is a common and irreversible loss of renal function. Renal fibrosis reflected the degree of renal dysfunction. However, the current biomarkers only characterize the renal function instead of indicating the fibrosis degree.

A Clinical-Radiomics Nomogram Based on Magnetic Resonance Imaging for Predicting Progression-Free Survival After Induction Chemotherapy in Nasopharyngeal Carcinoma.

Purpose: This paper aimed to establish and verify a radiomics model based on magnetic resonance imaging (MRI) for predicting the progression-free survival of nasopharyngeal carcinoma (NPC) after induction chemotherapy (IC).

Materials And Methods: This cohort consists of 288 patients with clinical pathologically confirmed NPC, which was collected from January 2015 to December 2018. All NPC patients were randomly divided into two cohorts: training (n=202) and validation (n=86).

MRI-based random survival Forest model improves prediction of progression-free survival to induction chemotherapy plus concurrent Chemoradiotherapy in Locoregionally Advanced nasopharyngeal carcinoma.

Background: The present study aimed to explore the application value of random survival forest (RSF) model and Cox model in predicting the progression-free survival (PFS) among patients with locoregionally advanced nasopharyngeal carcinoma (LANPC) after induction chemotherapy plus concurrent chemoradiotherapy (IC + CCRT).

Methods: Eligible LANPC patients underwent magnetic resonance imaging (MRI) scan before treatment were subjected to radiomics feature extraction. Radiomics and clinical features of patients in the training cohort were subjected to RSF analysis to predict PFS and were tested in the testing cohort.

Single-Component White Light Emission from a Metal-Coordinated Cyclotriveratrylene-Based Coordination Polymer.

A coordination polymer, namely, [CdL(HO)]·DMA·4HO () (DMA = ,-dimethylacetamide), was prepared by the solvothermal reaction of cyclotriveratrylene-based ligand 5,6,12,13,19,20-hexacarboxy-methoxy-cyclotriveratrylene (HL) and Cd(NO)·4HO. In , a two-dimensional structure was constructed by the connection of hexanuclear Cd-O clusters and L anions. Photoluminescence measurements indicated that displayed tunable photoluminescence through the variation of the excitation wavelength.

Enhanced Fluorescence with Tunable Color in Doped Diphosphine-Protected Gold Nanoclusters.

Rational control of the luminescent properties of ligand-protected coinage metal clusters has long been pursued but remains challenging. Here we explore the crucial structural and electronic factors governing the fluorescence of a diphosphine-protected [Au(dppe)Cl] cluster by time-dependent density functional theory calculations. By substituting the central Au atom with group 5 to group 11 transition metal atoms, the emission wavelength is adjustable from red to blue, accompanied by enhanced fluorescence intensity compared with the undoped cluster.