The ventromedial hypothalamic nucleus plays an important role in anxiolytic-like effect of neuropeptide S.

Neuropeptide S (NPS), the endogenous neuropeptide ligand of NPSR, has been reported to regulate anxiety-related behavior involved in multiple brain regions, including amygdale, locus coeruleus and Barrington's nucleus. However, little research has been conducted on the anxiolytic-like behaviors of NPS on the hypothalamus, which was an important area in defensive behavior. Here, we investigated a role of hypothalamus in anxiolytic-like behaviors of NPS.

Two-port laparoscopic cholecystectomy with modified suture retraction of the fundus: A practical approach.

Context: Although transumbilical single incision laparoscopic cholecystectomy (SILC) has been demonstrated to be superior cosmetic, it is only limited to simple cases at present. In complex cases, the standard four- or three-port LC is still the treatment of choice.

Aim: To summarize the clinical effect of a modified technique in two-port LC.

Investigation of EscA as a chaperone for the Edwardsiella tarda type III secretion system putative translocon component EseC.

Edwardsiella tarda is an important Gram-negative enteric pathogen affecting both animals and humans. It possesses a type III secretion system (T3SS) essential for pathogenesis. EseB, EseC and EseD have been shown to form a translocon complex after secretion, while EscC functions as a T3SS chaperone for EseB and EseD.

[Expression pattern of profilin homologue in embryogenesis of amphioxus].

The expression pattern of profilin homologue in embryogenesis of amphioxus was characterized by whole-mount in situ hybridization combined serial histological sections and Northern blot. The results revealed that the dynamic expression pattern of the profilin homologue just accorded with muscle differentiating in this animal. It was most possibly involved in the development of muscle in amphioxus.