Qualification of the Geenius HIV 1/2 supplemental assay for use in the HIV blood donation screening algorithm.

Background: A single, simplified approach for human immunodeficiency virus (HIV)-1/HIV-2 antibody confirmation/differentiation is needed for the HIV blood donation supplemental algorithm used in the United States. A clinical evaluation of the Geenius assay was performed-the same assay used for HIV diagnostic confirmation/differentiation in the United States since 2014.

Study Design And Methods: Well-characterized unlinked donation samples classified as HIV negative, false positive, or confirmed positive were included in the study: 200 antibody-nonreactive, 200 HIV-1 immunofluorescence assay (IFA) confirmed-positive, and 100 antibody-screen false-positive donations, equally divided between serum and plasma.

Is environmental tobacco smoke exposure a risk factor for acute gastroenteritis in young children?

Because passive smoke exposure has not been previously linked to diarrhea diseases in children, it was hypothesized that very young children exposed to environmental tobacco smoke (ETS) exposure at home would also be more likely to develop infectious gastroenteritis (GE) than their unexposed counterparts. During 1-year period, 260 children 36 months and younger were prospectively followed up in a private pediatric practice in a southern community in the United States. Multiple logistic regression analysis showed that ETS was strongly predictive of acute GE in the univariate analysis (P = .

Black/white differential use of health services by young children in a rural Mississippi community.

Background And Objectives: Use of health services in rural communities has not been well studied. We explored how black and white children used health services in a rural Mississippi community.

Methods: Data were prospectively collected for 396 children attending a private practice to determine if race was associated with the use of health services in this community.