Publications by authors named "Peggy Lee"

Objective(s): To determine the most repeatable ultrasound imaging protocols for assessing the masseter muscle, evaluating repeatability across different scan locations, muscle contraction states, and operator positions.

Study Design: Ten adult volunteers underwent ultrasound scans, including three axial (superior/middle/inferior) and three longitudinal (anterior/middle/posterior) views on the left and right sides and in the relaxed and clenched states. Each subject was scanned twice, roughly 15 minutes apart.

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  • Jaw and maxillofacial bone lesions include various neoplastic and non-neoplastic pathologies that can originate from bone, cartilage, and soft tissue, making diagnosis and treatment complex.
  • Many lesions have distinct imaging characteristics, but some are nonspecific, requiring a combination of imaging techniques like radiographs, CT, and MRI for accurate diagnosis.
  • The article reviews imaging approaches for these tumors and provides updates on the 2022 World Health Organization classification, along with essential anatomy for better imaging interpretation.
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  • Juvenile dermatomyositis (JDM) is a rare childhood autoimmune disease potentially linked to microbial exposure, prompting a study on its association with oral and gut microbiome differences.
  • In this study, researchers analyzed microbiome samples from JDM patients and their unaffected family members to understand the impact of genetics and environment on microbiome diversity.
  • Findings indicated that JDM patients had microbiomes more similar to their unaffected siblings than to other JDM patients, with specific bacterial differences potentially influencing the disease's development or being a result of immune dysfunction.
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Background: The current domestic nursing workforce is the most generational diversity in history with a wide range of life experiences.

Purpose: The purpose of this study was to investigate generational differences in organizational commitment, job satisfaction and personality traits in a sample of nursing students preparing for the workforce.

Methods: This cross-sectional study used data collected from pre-licensure final semester nursing students and degree completion students (n = 313) from three different schools about job satisfaction, personality traits and organizational commitment.

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Osteoblastoma and osteoid osteoma are rare benign neoplasms of the jaws. We reviewed current literature surrounding the ongoing debate over similarities and differences of osteoblastoma and osteoid osteoma and present two cases. Both cases are well-demarcated mixed radiodensity mandibular lesions with histological features of osteoblastoma.

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  • Adenoid cystic carcinoma (ACC) frequently spreads perineurally, leading to delays in diagnosis and treatment due to misinterpretations of symptoms like pain and numbness.
  • A study of 44 patients revealed that a significant number were initially evaluated for dental issues and that perineural spread (PNS) was identified in 81.8% of cases, particularly correlating with paresthesia.
  • The research highlights a concerning trend where patients often face an average delay of 18.3 months from the onset of symptoms to an accurate diagnosis, emphasizing the need for improved diagnostic awareness among healthcare providers.
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Osteopetrosis (marble bone disease) is a family of rare genetic disorders characterized by impaired osteoclast function leading to hyperdense, hypovascular, brittle bone. Typical imaging shows increased bone mass and thickened cortical and trabecular bone. Bones are more prone to fracture and osteomyelitis may develop.

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Background: The oral microbiota has been implicated in the pathogenesis of rheumatoid arthritis through activation of mucosal immunity. This study tested for associations between oral health, microbial communities and juvenile idiopathic arthritis (JIA).

Methods: A cross-sectional exploratory study of subjects aged 10-18 years with oligoarticular, extended oligoarticular and polyarticular JIA was conducted.

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Background: The research findings about nurse practitioner (NP) patient experiences (satisfaction) are limited to small sample sizes from local community clinics. No national studies with large sample sizes were found.

Purpose: To analyze responses from the Consumer Assessment of Healthcare Providers and Systems survey and compare the patient experiences from four different provider categories.

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Objective: Our previous study of patients with unilateral temporomandibular joint (TMJ) osteoarthritis (OA) showed that the affected joints had greater horizontal condylar angle (HCA) compared with the contralateral unaffected joints. However, it was unclear whether the HCA changes preceded or were the result of OA changes. The aim of this longitudinal study was to investigate the relationship between HCA and OA progression.

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Background: Massive occurrences of interstitial loss of heterozygosity (LOH) likely resulting from gene conversions were found by us in different cancers as a type of single-nucleotide variations (SNVs), comparable in abundance to the commonly investigated gain of heterozygosity (GOH) type of SNVs, raising the question of the relationships between these two opposing types of cancer mutations.

Methods: In the present study, SNVs in 12 tetra sample and 17 trio sample sets from four cancer types along with copy number variations (CNVs) were analyzed by AluScan sequencing, comparing tumor with white blood cells as well as tissues vicinal to the tumor. Four published "nontumor"-tumor metastasis trios and 246 pan-cancer pairs analyzed by whole-genome sequencing (WGS) and 67 trios by whole-exome sequencing (WES) were also examined.

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The need for registered nurses in the United States continues to grow. To meet this need for increased numbers of nurses, recruitment and retention of qualified nurse educators has become a priority. In addition, the factors associated with nursing faculties' intent to stay have emerged as important considerations for administrators.

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Background: Research using magnetic resonance imaging analysis has shown that internal temporomandibular joint derangement is associated with significantly greater horizontal condylar angle. However, the association between osteoarthritic (OA) bony changes as shown on computed tomography and horizontal condylar angle has never been evaluated.

Objective: To investigate the relationship between mandibular condylar angle and OA degenerative changes.

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Objectives: This study identified the difference in energy expenditure and substrate utilization of patients during and upon liberation from mechanical ventilation.

Methods: Patients under intensive care who were diagnosed with septic shock and dependent on mechanical ventilation were recruited. Indirect calorimetry measurements were performed during and upon liberation from mechanical ventilation.

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Background: In nursing education, the academic administrator is critical given the multitude of challenges associated with program delivery (e.g., shortages of faculty, strict and changing regulations for program accreditation, and the sheer demand for more nurses).

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P1 Serologic evidence of gut-driven systemic inflammation in juvenile idiopathic arthritis Lampros Fotis, Nur Shaikh, Kevin Baszis, Anthony French, Phillip Tarr P2 Oral health and anti-citrullinated peptide antibodies (ACPA) in juvenile idiopathic arthritis Sriharsha Grevich, Peggy Lee, Sarah Ringold, Brian Leroux, Hannah Leahey, Megan Yuasa, Jessica Foster, Jeremy Sokolove, Lauren Lahey, William Robinson, Joshua Newsom, Anne Stevens P3 Novel autoantigens for endothelial cell antibodies in pediatric rheumatic diseases identified by proteomics Rie Karasawa, Mayumi Tamaki, Megumi Tanaka, Toshiko Sato, Kazuo Yudoh, James N. Jarvis P4 Transcriptional profiling reveals monocyte signature associated with JIA patient poor response to methotrexate Halima Moncrieffe, Mark F. Bennett, Monica Tsoras, Lorie Luyrink, Huan Xu, Sampath Prahalad, Paula Morris, Jason Dare, Peter A.

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Background: The presence of loss-of-heterozygosity (LOH) mutations in cancer cell genomes is commonly encountered. Moreover, the occurrences of LOHs in tumor suppressor genes play important roles in oncogenesis. However, because the causative mechanisms underlying LOH mutations in cancer cells yet remain to be elucidated, enquiry into the nature of these mechanisms based on a comprehensive examination of the characteristics of LOHs in multiple types of cancers has become a necessity.

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When measurement of resting metabolic rate (RMR) by indirect calorimetry is necessary, following evidence-based protocols will ensure the individual has achieved a resting state. The purpose of this project was to update the best practices for measuring RMR by indirect calorimetry in healthy and non-critically ill adults and children found the Evidence Analysis Library of the Academy of Nutrition and Dietetics. The Evidence Analysis process described by the Academy of Nutrition and Dietetics was followed.

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Objective: The goal of this study was to detect dimensional changes in the mandibular cortical bone associated with bisphosphonate (BP) use and to correlate measurements of the cortical bone with the cumulative dose of BPs.

Study Design: Mandibular inferior cortical bone thickness (MICBT) was measured under the mental foramen on panoramic radiographs of patients with and without bisphosphonate-related osteonecrosis of the jaws (BRONJ) taking BPs and controls.

Results: Patients with BRONJ had the highest mean MICBT (6.

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Objectives: The objective of this study was to develop a technique for detecting cortical bone dimensional changes in patients with bisphosphonate-related osteonecrosis of the jaw (BRONJ).

Study Design: Subjects with BRONJ who had cone-beam computed tomography imaging were selected, with age- and gender-matched controls. Mandibular cortical bone measurements to detect bisphosphonate-related cortical bone changes were made inferior to mental foramen, in 3 different ways: within a fixed sized rectangle, in a rectangle varying with the cortical height, and a ratio between area and height.

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Cutaneous diphtheria is a rare infection in the United States. This article presents a case of genital ulcerations, which were likely secondary to cutaneous coryneform bacterial infection, and reviews the literature concerning the diagnosis and management of this entity. In addition, we briefly review other Gram-positive Bacillus bacterial infections of the skin.

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It is estimated that 78% of projects fail to meet their original objectives. The time spent on project planning will help to improve on this statistic and directly yield a more successful project outcome. Based on the experiences of a panel of experts and the authors' experiences, this article presents a detailed planning guide to increase the chances of success on health care software implementations.

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Basaloid follicular hamartoma syndrome (BFHS) is a rare adnexal tumor genodermatosis. We present a case of hereditary BFHS and review the literature concerning the clinical and histologic features of this entity.

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