Lactobacillus crispatus-dominated vaginal microbiome and Acinetobacter-dominated seminal microbiome support beneficial ART outcome.

Introduction: Despite the considerable progress made in assisted reproductive technologies (ART), the implantation rate of transferred embryos remains low and in many cases, the reasons for failure remain unclear. We aimed to determine the potential impact of female and male partners' reproductive tract microbiome composition on ART outcome.

Material And Methods: The ART couples (n = 97) and healthy couples (n = 12) were recruited into the study.

VNTR I/I genotype of insulin gene is associated with the increase of follicle number independent from polycystic ovary syndrome.

Background: Polycystic ovary syndrome (PCOS) is accompanied by selective insulin resistance and enhanced ovarian steroidogenic effects of insulin. We analysed the minisatellite variations of the insulin gene (INS VNTR) with regard to the clinical features of PCOS.

Methods: Retrospective, adjusted association study.