Publications by authors named "Pedro-Marques Vidal"

: Timely and appropriate outpatient care can prevent potentially avoidable hospitalizations (PAHs) for heart failure (HF). We analyzed the trends, determinants, and consequences of PAHs for HF in Switzerland over two decades.; : Hospital discharge data of Switzerland from 1998 to 2018 were utilized.

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We aimed to identify and validate factors related to uncontrolled hypertension. Participants treated with at least one antihypertensive drug from the prospective contemporaneous CoLaus|PsyCoLaus study were enrolled. We investigated the association between hypertension status (uncontrolled, defined as systolic blood pressure [SBP] ≥ 140 mm Hg and/or diastolic blood pressure [DBP] ≥ 90 mm Hg, versus controlled hypertension [SBP/DBP < 140/90 mm Hg]) and potential risk factors.

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Background: An unhealthy diet is a major contributor to several noncommunicable diseases, including cardiovascular diseases (CVD), the leading cause of death worldwide. Additionally, our food system has significant impacts on the environment. The EAT-Lancet Commission has recommended a healthy diet that preserves global environmental resources.

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Background: Timely and appropriate outpatient care can prevent potentially avoidable hospitalizations (PAH) for diabetes. We analysed the trends, determinants, and consequences of PAH for diabetes in Switzerland over two decades.

Methods: hospital discharge data for years 1998-2018 were used.

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In face of cumulating evidence about the impact of human-induced environmental changes on mental health and behavior, our understanding of the main effects and interactions between environmental factors - i.e., the exposome and the brain - is still limited.

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Article Synopsis
  • - The ToxiLaus study investigates how environmental trace elements (TEs) affect human health, particularly their role in disease onset and development.
  • - The initial phase focused on measuring the urinary concentrations of 23 TEs in over 5,800 participants and examining their associations with smoking, metabolic syndrome, and body mass index (BMI).
  • - Key findings included that smoking status and metabolic syndrome were linked to specific TEs like Cd and Zn, and significant differences in TEs concentrations were found across different BMI groups, paving the way for further analysis in later phases.
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  • Dietary supplements are products with vitamins, minerals, or other substances meant to enhance diets, but they can be sold without proven effectiveness or safety.
  • In Switzerland, about a third of people use DS to boost health, but scientific evidence on their benefits for serious conditions is inconsistent.
  • Overall, health benefits of dietary supplements appear to be minimal or nonexistent, and regular use is not recommended for healthy adults.
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Background And Aims: Vitamin/mineral supplements (VMS) and vitamin/mineral and/or dietary supplements (VMDS) are commonly consumed, based on the belief of their invigorating properties. Still, the association of VMS/VMDS with fatigue in the general population remains sparse and conclusions are mixed. This study aimed to understand the association between VMS/VMDS and fatigue.

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  • A study analyzed the prevalence and treatment of hypertension (HTN) in solid organ transplant recipients over five years, focusing on kidney, heart, lung, and liver transplants.
  • The study found high rates of HTN, with prevalence ranging from 61.8% to 90.4% at different time points, and identified significant cases of uncontrolled HTN particularly in kidney, liver, and lung transplant recipients.
  • Uncontrolled HTN poses a serious risk after transplantation, emphasizing the need for better management strategies, especially among liver and lung transplant patients who may not have pre-existing cardiovascular problems.
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Background: Moderate-intensity physical activity (PA) is recommended for health benefits, but optimal PA timing regarding cardiovascular disease (CVD) is debated.

Objectives: The authors assessed the impact of differing PA patterns on CVD risk factors and outcomes.

Methods: Data from 2 surveys (S1 and S2) of the CoLaus-PsyCoLaus study (2,465 and 1,692 participants, respectively; 55.

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Introduction: Physical activity (PA) is recommended in patients with type 2 diabetes mellitus (T2DM) to improve their glycaemic control. We aimed to assess PA levels among participants with controlled and uncontrolled T2DM.

Research Design And Methods: Three cross-sectional analyses of a prospective cohort conducted in Lausanne, Switzerland.

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Introduction: Appropriate cooking methods can improve food safety, decrease contaminants, and increase nutrient bioavailability. Few studies assessed the sociodemographic characterization of their use in European populations. We aimed to characterize the socio-demographic, lifestyle, and anthropometric predictors of cooking methods in the Swiss population.

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Background: Targeting effective strategies to prevent cognitive decline is key in the aging population. Some diets have been linked to a slower cognitive decline, potentially through reducing inflammation. We aimed at determining the effect of inflammatory dietary patterns (IDPs) on cognitive function in three population-based cohorts.

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Objective: Liver cirrhosis is an increasing cause of morbidity and mortality worldwide with a heavy load on healthcare systems. We analysed the trends in hospitalisations for cirrhosis in Switzerland.

Design: Cross-sectional study.

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Background: Meat consumption could increase the risk of type 2 diabetes. However, evidence is largely based on studies of European and North American populations, with heterogeneous analysis strategies and a greater focus on red meat than on poultry. We aimed to investigate the associations of unprocessed red meat, processed meat, and poultry consumption with type 2 diabetes using data from worldwide cohorts and harmonised analytical approaches.

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We assessed the trends, characteristics, and consequences of potentially avoidable hospitalizations (PAH) for hypertension in Switzerland, for the period 1998 to 2018. Data from 117,507 hospitalizations (62.1% women), minimum age 20 years.

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Research on antidepressant-related weight changes over more than 12 months is scarce and adjustment for the effects of depressive episodes has rarely been applied. Accordingly, our aim was to assess the associations of the use of any antidepressants, subclasses of antidepressant and specific compounds prior to baseline and during a 5.5-year follow-up with changes in adiposity markers, and the effect of sex on these associations, with adjustment for multiple confounders including the effects of depressive episodes and their severity.

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Although both short and long sleep duration are associated with elevated hypertension risk, our understanding of their interplay with biological pathways governing blood pressure remains limited. To address this, we carried out genome-wide cross-population gene-by-short-sleep and long-sleep duration interaction analyses for three blood pressure traits (systolic, diastolic, and pulse pressure) in 811,405 individuals from diverse population groups. We discover 22 novel gene-sleep duration interaction loci for blood pressure, mapped to 23 genes.

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Background: The association between dairy intake and prevalence or incidence of hypertension remains controversial. We aimed to investigate the association between intake of different dairy products and prevalence and incidence of hypertension in a community-dwelling sample.

Methods: Three cross-sectional studies (2009-12, 2014-17 and 2018-21) and one prospective study (2009-12 to 2018-21) were conducted in Lausanne, Switzerland.

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Background: Various surrogate markers of insulin resistance have been developed, capable of predicting coronary artery disease (CAD) without the need to detect serum insulin. For accurate prediction, they depend only on glucose and lipid profiles, as well as anthropometric features. However, there is still no agreement on the most suitable one for predicting CAD.

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Article Synopsis
  • The study investigates how accelerometry data, covering sleep, physical activity, and circadian rhythms, relates to mood disorders like major depressive disorder (MDD), moving beyond traditional research that often examined these factors in isolation.
  • The Joint and Individual Variation Explained (JIVE) method was used to analyze data from 2,317 adults in Switzerland, identifying key components from accelerometry data linked to both current and remitted MDD.
  • Results indicated that certain joint components explain a significant portion of variation in sleep and activity patterns, with distinct associations found between these components and both ongoing and past depressive states.
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  • This study investigates how iron markers might influence the relationship between biological sex and the risk of developing type 2 diabetes (T2D).
  • Researchers analyzed health data from a large group of individuals in the Netherlands, measuring various iron-related biomarkers and glucose levels.
  • Results showed that females generally had lower glucose levels and a lower incidence of T2D compared to males, with certain iron biomarkers (like ferritin) partially explaining these differences.
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  • * Key findings showed that higher scores on the Epworth Sleepiness Scale and the presence of insomnia symptoms were associated with a greater risk of developing MDD, with specific hazard ratios calculated for both factors.
  • * Notably, men with increased rapid eye movement (REM) sleep had a higher MDD incidence, while women with higher delta power in their sleep showed a lower incidence, indicating gender differences in how sleep affects depression risk.
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Background: The association between iron biomarkers and cardiovascular disease risk factors (CVD-RFs) remains unclear. We aimed to (1) evaluate the cross-sectional and longitudinal associations between iron biomarkers (serum ferritin, transferrin saturation (TSAT), transferrin) and CVD-RFs among women, and (2) explore if these associations were modified by menopausal status.

Method: Cross-sectional and longitudinal analyses including 2542 and 1482 women from CoLaus cohort, respectively.

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