Global end-diastolic volume could be more appropiate to reduce intraoperative bleeding than central venous pressure during major liver transection.

Background: Central venous pressure often fails to identify the true value of cardiac preload. Our purpose is to investigate whether Global End-Diastolic Volume (GEDV) values can control hemodynamic parameters for the measurement of fluid volume, cardiac preload and blood loss during liver transection.

Methods: This was a prospective clinical study that included patients undergoing liver resection.