Characterization and prediction of the clinical result with a specific model of mini-scleral contact lens in corneas with keratoconus.

Background: To investigate which factors are correlated with the visual improvement achieved with a specific model of scleral contact lens (SCL) in keratoconus (KC) eyes and to define a model to predict such improvement according to the pre-fitting data. In addition, the changes occurred with the fitting of a specific model of SCL during a period of 3 months in corneas with KC have been investigated.

Methods: Longitudinal retrospective study including 30 eyes of 18 patients (age, 14-65 years) with KC fitted with the SCL ICD16.

Characterization of Dysfunctional Lens Index and Opacity Grade in a Healthy Population.

This study enrolled 61 volunteers (102 eyes) classified into subjects < 50 years (group 1) and subjects ≥ 50 years (group 2). Dysfunctional Lens Index (DLI); opacity grade; pupil diameter; and corneal, internal, and ocular higher order aberrations (HOAs) were measured with the i-Trace system (Tracey Technologies). Mean DLI was 8.

Efficacy of Perceptual Learning-Based Vision Training as an Adjuvant to Occlusion Therapy in the Management of Amblyopia: A Pilot Study.

A retrospective study was conducted to evaluate preliminarily the efficacy of perceptual learning (PL) visual training in medium-term follow-up with a specific software (Amblyopia iNET, Home Therapy Systems Inc., Gold Canyon, AZ, USA) for visual acuity (VA) and contrast sensitivity (CS) recovering in a sample of 14 moderate to severe amblyopic subjects with a previously unsuccessful outcome or failure with patching (PL Group). This efficacy was compared with that achieved in a patching control group (13 subjects, Patching 2).

Analysis of Intrasession Repeatability of Ocular Aberrometric Measurements and Validation of Keratometry Provided by a New Integrated System in Mild to Moderate Keratoconus.

Purpose: To evaluate the intrasession repeatability and validity of corneal curvature measurements provided by a new multifunctional device and to assess the intrasession repeatability of its ocular aberrometric measures.

Methods: This prospective study comprises 37 mild to moderate keratoconus eyes of 37 patients. In all cases, 3 repeated measures of corneal topography and ocular aberrometry were performed with the iDesign 2 system (iD2; Johnson & Johnson Vision Care Inc, Jacksonville, FL) and one keratometric measurement was performed with the intraocular lens-(IOL) Master 500 (Carl Zeiss Meditec Inc, Dublin, CA) and Sirius (CSO) (SIR) systems.

Interchangeability of corneal curvature and asphericity measurements provided by three different devices.

Aim: To evaluate the interchangeability of keratometric and asphericity measurements provided by three measurement systems based on different optical principles.

Methods: A total of 40 eyes of 40 patients with a mean age of 34.1y were included.

Differences in corneo-scleral topographic profile between healthy and keratoconus corneas.

Purpose: To evaluate the differences in corneo-scleral topographic profile between healthy and keratoconus eyes, and their potential diagnostic ability for keratoconus detection.

Methods: Prospective comparative study including 21 keratoconic eyes (11 patients) and 88 healthy eyes (88 patients). In all cases, a complete eye exam was performed including an evaluation of the corneo-scleral profile.

Usefulness of bandage contact lenses in the immediate postoperative period after uneventful myopic LASIK.

Purpose: To determine the usefulness of a silicone-hydrogel bandage contact lens (BCL) in the immediate postoperative period after uneventful myopic laser in-situ keratomileusis (LASIK).

Methods: The study design was randomized but not masked and data collection was prospective. This study comprised 51 consecutive myopic eyes intervened by means of the LASIK technique to compensate their refractive error.

Clinical outcomes at one year following keratoconus treatment with accelerated transepithelial cross-linking.

This study evaluated the clinical outcomes in keratoconus corneas following accelerated transepithelial corneal collagen cross-linking (CXL) (Avedro KXL system, Waltham, MA, USA) over one year of follow-up. The mean depth of the demarcation line measured by optical coherence tomography (OCT) was 205.19 µm.

Evaluation of the diagnostic ability of vector parameters characterizing the corneal astigmatism and regularity in clinical and subclinical keratoconus.

Purpose: To evaluate the diagnostic ability of the vector parameters ocular residual astigmatism (ORA), topography disparity (TD) and topographic astigmatism CorT (anterior and total) for the detection of clinical and subclinical keratoconus, and to develop a detection model based on them.

Methods: This study comprised a total of 61 keratoconus eyes (KC group), 19 eyes with subclinical keratoconus (SKC group) and 100 healthy eyes (control group). In all cases, a complete eye exam was performed including an analysis of the corneal structure with the Sirius system (Costruzione Strumenti Oftalmici, CSO).

Clinical Validation of Adjusted Corneal Power in Patients with Previous Myopic Lasik Surgery.

Purpose. To validate clinically a new method for estimating the corneal power (P c ) using a variable keratometric index (n kadj) in eyes with previous laser refractive surgery. Setting.

Comparative analysis of the visual performance and aberrometric outcomes with a new hybrid and two silicone hydrogel multifocal contact lenses: a pilot study.

Background: The aim was to evaluate the visual performance achieved with a new multifocal hybrid contact lens and to compare it with that obtained with two other currently available multifocal soft contact lenses.

Methods: This pilot prospective comparative study comprised a total of 16 presbyopic eyes of eight patients ranging in age from 43 to 58 years. All patients were fitted with three different models of multifocal contact lens: Duette multifocal (SynergEyes), Air Optix AQUA multifocal (Alcon) and Biofinity multifocal (CooperVision).

Clinical utility of ocular residual astigmatism and topographic disparity vector indexes in subclinical and clinical keratoconus.

Purpose: We aimed to characterize the distribution of the vector parameters ocular residual astigmatism (ORA) and topography disparity (TD) in a sample of clinical and subclinical keratoconus eyes, and to evaluate their diagnostic value to discriminate between these conditions and healthy corneas.

Methods: This study comprised a total of 43 keratoconic eyes (27 patients, 17-73 years) (keratoconus group), 11 subclinical keratoconus eyes (eight patients, 11-54 years) (subclinical keratoconus group) and 101 healthy eyes (101 patients, 15-64 years) (control group). In all cases, a complete corneal analysis was performed using a Scheimpflug photography-based topography system.

Intra-session repeatability of iridocorneal angle measurements provided by a Scheimpflug photography-based system in healthy eyes.

Purpose: The purpose of this study was to evaluate intra-session repeatability of measurements of the iridocorneal angle at different meridians in the nasal and temporal areas in healthy eyes using the Sirius Scheimpflug photography-based system in glaucoma analysis mode.

Methods: A total of 43 eyes of 43 patients ranging in age from 36 to 79 years were enrolled in the study. All eyes received a comprehensive ophthalmologic examination including a complete anterior segment analysis with the Costruzione Strumenti Oftalmici [CSO] Sirius system.

Influence of the difference between corneal and refractive astigmatism on LASIK outcomes using solid-state technology.

Purpose: To evaluate the influence of the difference between preoperative corneal and refractive astigmatism [ocular residual astigmatism (ORA)] on outcomes obtained after laser in situ keratomileusis (LASIK) surgery for correction of myopic astigmatism using the solid-state laser technology.

Methods: One hundred one consecutive eyes with myopia or myopic astigmatism of 55 patients undergoing LASIK surgery using the Pulzar Z1 solid-state laser (CustomVis Laser Pty Ltd, currently CV Laser) were included. Visual and refractive changes at 6 months postoperatively and changes in ORA and anterior corneal astigmatism and posterior corneal astigmatism (PCA) were analyzed.

New-generation hybrid contact lens for the management of extreme irregularity in a thin cornea after unsuccessful excimer laser refractive surgery.

Purpose: To report a very successful outcome obtained with the fitting of a new-generation hybrid contact lens of reverse geometry in a thin cornea with extreme irregularity due to the presence of a central island after unsuccessful myopic excimer laser refractive surgery.

Methods: A 32-year-old man attended to our clinic complaining of very poor vision in his right eye after bilateral laser in situ keratomileusis (treatment or surgery) for myopia correction and some additional retreatments afterward. After a comprehensive ocular evaluation, contact lens fitting with a reverse geometry hybrid contact lens (SynergEyes PS, SynergEyes, Carlsbad, CA) was proposed as a solution for this case.

Ocular residual astigmatism and topographic disparity vector indexes in normal healthy eyes.

Purpose: To define a range of normality for the vectorial parameters Ocular Residual Astigmatism (ORA) and topography disparity (TD) and to evaluate their relationship with visual, refractive, anterior and posterior corneal curvature, pachymetric and corneal volume data in normal healthy eyes.

Methods: This study comprised a total of 101 consecutive normal healthy eyes of 101 patients ranging in age from 15 to 64 years old. In all cases, a complete corneal analysis was performed using a Scheimpflug photography-based topography system (Pentacam system Oculus Optikgeräte GmbH).

Pilot study of hyperopic LASIK using the solid-state laser technology.

Background: To evaluate and report the visual, refractive, and aberrometric outcomes of LASIK for the correction of low to moderate hyperopia in a pilot group using a commercially available solid-state laser

Methods: Prospective pilot study including 11 consecutive eyes with low to moderate hyperopia of six patients undergoing LASIK surgery using the Pulzar Z1 solid-state laser (CustomVis Laser Pty Ltd., currently CV Laser). Visual, refractive, and aberrometric changes were evaluated.

Clinical validation of an algorithm to correct the error in the keratometric estimation of corneal power in normal eyes.

Purpose: To validate clinically in a normal healthy population an algorithm to correct the error in the keratometric estimation of corneal power based on the use of a variable keratometric index of refraction (n(k)).

Setting: Medimar International Hospital (Oftalmar) and University of Alicante, Alicante, Spain.

Design: Case series.