Introduction: Hyperuricemia (HU) is associated with an increased risk of incident heart failure (HF) and adverse HF outcomes. Patients with diabetes mellitus (DM) have a greater prevalence of HU.
Aims: We evaluated the prognostic impact of HU in patients with HF according to the coexistence of DM.
Background: Increased levels of platelet distribution width (PDW) can predict cardiac death and infarction recurrence in acute myocardial infarction. PDW appears to be a prognosis marker in acute heart failure (HF); however, its impact on chronic HF is still unknown. We investigated the impact of PDW on chronic HF.
View Article and Find Full Text PDFBackground: Patients with heart failure often have multiple cardiovascular risk factors (CVRFs) and comorbidities (CMBs). We evaluated the impact of additive CMB and CVRF on heart failure prognosis.
Methods: We retrospectively analyzed ambulatory patients with systolic dysfunction between January 2012 and May 2018.
Unlabelled: Leptospirosis is a zoonotic infection infrequently reported in non-tropical regions. Although classically described as a biphasic illness, unusual clinical manifestations have been reported, including a previous case of a lung abscess associated with this causative agent. We present the case of a 49-year-old man with a new diagnosis of two liver abscesses associated with leptospirosis.
View Article and Find Full Text PDFIntroduction: The prognostic implications of using benzodiazepines (BZD) in heart failure (HF) patients are still unknown.
Objectives: This study aimed to assess the association of BZD use with all‑cause death in ambulatory, chronic HF patients.
Patients And Methods: We investigated a retrospective cohort of ambulatory HF patients with left ventricular systolic dysfunction (LVSD).
Eur J Case Rep Intern Med
November 2022
Unlabelled: Pulmonary arterial hypertension (PAH) is an increasingly recognised clinical entity that is associated with connective tissue disease (CTD) in up to one quarter of all diagnoses. Sjögren's syndrome (SS) is a chronic autoimmune disease characterised by ocular and oral dryness resulting from lacrimal and salivary gland dysfunction. Additionally, SS may involve virtually any organ system and, as a result, the disease is characterised by pleomorphic clinical manifestations.
View Article and Find Full Text PDFUnlabelled: Uveo-meningeal syndromes are any disorder characterized by the involvement of the uvea and the meninges. They can have multiple causes, including infectious, autoimmune and malignant diseases. We report the case of a patient with a 10-year-old diagnosis of myelodysplastic syndrome that had been stable.
View Article and Find Full Text PDFAims: Interleukin-6 (IL-6) is upregulated in response to infectious and inflammatory triggers and independently predicts all-cause mortality in acute heart failure (AHF). However, the association of IL-6 with cardiovascular outcomes and its interplay with C-reactive protein and infection, a major precipitating factor in AHF, remains poorly understood.
Methods And Results: The association between IL-6 and clinical outcomes (180 days) in AHF was evaluated using a cohort of 164 patients from the EDIFICA registry.
Objective: The aim of our systematic review was to update the current evidence on the association between slow walking speed (WS) and mortality, expanding the current knowledge available in the literature.
Methods: A systematic review of the published data on the association of WS and mortality was carried out by searching on PubMed and ISI Web of Knowledge databases.
Results: From a title and abstract analysis, 61 articles were included that met the prespecified criteria.
J Stroke Cerebrovasc Dis
August 2021
The development of SARS-CoV-2 vaccines has raised several concerns regarding venous thromboembolism, namely cerebral venous thrombosis. Although cerebral venous thrombosis has been reported after administration of a viral vector vaccine, due to a possible auto-immune mechanism inducing thrombocytopenia, the same has not happened in mRNA vaccines. We report two cases of cerebral venous thrombosis, shortly after administration of mRNA vaccine.
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