Publications by authors named "Pedro Paulo Faust Machado"
High-dose extended-field radiotherapy plus chemotherapy improved survival in extranodal NK/T-cell lymphoma in a real-life setting: results from the multicenter T-Cell Brazil Project.
Luís Alberto de Pádua Covas Lage Pedro Paulo Faust Machado Cadiele Oliana Reichert Eliana Miranda Hebert Fabrício Culler
Sci Rep
November 2022
Article Synopsis
- Extranodal natural-killer/T-cell lymphoma (ENKTL) is a rare and aggressive cancer linked to Epstein-Barr virus, prevalent in South America, but limited studies have been conducted on patients from this region.
- A retrospective study of 98 ENKTL patients from Brazil revealed that most were male, with a median age of 50; common symptoms included B-symptoms, and a significant portion were diagnosed at advanced stages.
- Treatment outcomes indicated a median overall survival of 21.8 months for early-stage patients treated with certain regimens, while advanced-stage patients had much lower survival rates; combination therapies produced better survival outcomes compared to chemotherapy alone.