Publications by authors named "Pedro Paulo A Manso"

Article Synopsis
  • Viruses, like SARS-CoV-2, rely on their host's cell machinery for replication, making host pathways potential targets for therapies.
  • Monocytes from COVID-19 patients show increased lipid droplet (LD) accumulation, which the virus uses to enhance lipid synthesis and facilitate its own replication.
  • Inhibition of LD formation through specific pharmacological agents significantly reduces SARS-CoV-2 replication and inflammation, suggesting new avenues for treating COVID-19.
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Dentigerous cyst (DC) and keratocystic odontogenic tumor (KOT) are odontogenic lesions arising from epithelial elements, such as those observed in dental follicles (DF), that have been part of the tooth forming apparatus. These lesions show different clinical and histological characteristics, as well as distinct biological behavior. This study aimed to qualify and quantify collagen and elastic fibers by means of histochemical techniques with light and confocal laser microscopic methods in three odontogenic entities.

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Schistosomiasis is a water-borne parasitic illness caused by neoophoran trematodes of the genus Schistosoma. Using classical histological techniques and whole-mount preparations, the present work describes the embryonic development of Schistosoma mansoni eggs in the murine host and compares it with eggs maintained under in vitro conditions. Two pre-embryonic stages occur inside the female worm: the prezygotic stage is characterized by the release of mature oocytes from the female ovary until its fertilization.

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