Popper's conjecture with angular slits and twisted light.

Uncertainty relations are core to both classical and quantum physics, and lend themselves to tests across many degrees of freedom, with structured light emerging as a vibrant tool to harness these degrees of freedom. Here, we test Popper's conjecture by replacing the traditional spatial and momentum states with angular position and orbital angular momentum (OAM) states of photons, showing that the OAM spectrum for an entangled photon passing through a virtual slit differs from that of a photon passing through a physical slit. To achieve this, we produce two OAM entangled photons, one of which is sent to a slit encoded as a digital hologram, thereby localising its angular position, all the while measuring the OAM of the other.

Synthetic spin dynamics with Bessel-Gaussian optical skyrmions.

Skyrmions are topologically stable fields that cannot be smoothly deformed into any other field configuration that differs topologically, that is, one that possesses a different integer topological invariant called the Skyrme number. They have been studied as 3-dimensional and 2-dimensional skyrmions in both magnetic and, more recently, optical systems. Here, we introduce an optical analogy to magnetic skyrmions and demonstrate their dynamics within a magnetic field.

Genetic polymorphisms and asthma: findings from a case-control study in the Madeira island population.

Background: Asthma is a complex disease influenced by multiple genetic and environmental factors. While Madeira has the highest prevalence of asthma in Portugal (14.6%), the effect of both genetic and environmental factors in this population has never been assessed.