Publications by authors named "Pedro M"

Article Synopsis
  • * A scoping review will investigate current stakeholder engagement practices in NCD IR within LMICs by utilizing a systematic screening process and thematic synthesis, focusing on studies published from 2011 onward.
  • * Ethical considerations are emphasized, including respect for original authors and data integrity, with plans for dissemination through various channels like peer-reviewed journals, conferences, and social media to share findings effectively.
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Background: During the past years, a bidirectional relationship has been proved between periodontitis and some systemic disorders, such as diabetes mellitus (DM) and cardiovascular diseases (CVDs). The aim of this study was to compare the general health status between patients with and without periodontitis from a Spanish university dental clinic.

Material And Methods: A retrospective observational case-control study was conducted to achieve the research objective.

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Nerve tumors in the retroperitoneal space are a rarity. Radical surgery according to soft tissue tumors can lead to persistent pain and neurological deficits. This study aims to evaluate clinical outcomes of patients treated by a visceral- / neurosurgical approach.

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Background: Neurology and literature have a complex interface; one of the facets is that of works inspired by grief on the passing of a beloved one due to a neurological disease.

Summary: In Memoriam A.H.

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  • Cardiac resynchronization therapy (CRT) using biventricular (BIV) pacing is aimed at heart failure patients but some don't respond; MultiPoint Pacing (MPP) might offer better results for these non-responders.
  • In a study with 3724 patients treated with BIV, 1639 were identified as non-responders and some were randomized to MPP or continued BIV pacing.
  • Results showed MPP led to better outcomes with a 33% success rate in reducing heart failure events compared to 23.5% in BIV, and MPP also resulted in fewer hospitalizations for heart failure.
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  • Peripheral nerve injuries can lead to the formation of neuromas, which are abnormal growths at the injury site that can stop nerves from healing properly.
  • Researchers studied human neuroma tissue and compared it to healthy nerves from the same person to understand what happens at the injury site over time (1-13 months after injury).
  • They found that even though the nerve repair cells called Schwann cells were present, they were in a "repair mode" and different from healthy cells, with signs of inflammation and reduced ability to form myelin, which is important for nerve function.
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  • - The study highlights that most peripheral nerve tumors are benign, primarily consisting of schwannomas and neurofibromas, but also discusses rare tumors and non-tumorous lesions that can mimic these conditions, based on data from a German registry of 315 patients.
  • - The cohort includes 61 cases of unusual tumors, showcasing a range of pathological features and biological potentials, with diagnoses like malignant peripheral nerve tumors, perineurioma, hybrid tumors, and various extrinsic lesions like lymphoma and hemangioma.
  • - A definitive preoperative diagnosis is often challenging, necessitating collaboration among specialists in radiology, neurology, neuropathology, and neurosurgery to improve diagnosis and treatment options for patients.
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Atherosclerotic cardiovascular disease (ASCVD) remains the major cause of premature death and disability; effective cardiovascular (CV) risk prevention is fundamental. The World Heart Federation (WHF) Cholesterol Roadmap provides a framework for national policy development and aims to achieve ASCVD prevention. At the invitation of the WHF, a group of experts from the Portuguese Society of Cardiology (SPC), addressed the cholesterol burden at nationally and discussed possible strategies to include in a Portuguese cholesterol roadmap.

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Background And Aims: In the United States, the opioid epidemic has led many young people who use opioids to initiate injection drug use, putting them at risk for hepatitis C virus (HCV) infection. However, community surveys to monitor HCV prevalence among young people who inject drugs (YPWID) are rare.

Methods: As part of Staying Safe (Ssafe), a trial to evaluate an HCV-prevention intervention, a community-recruited sample of 439 young people who use opioids (ages 18-30) in New York City (NYC) were screened from 2018 to 2021.

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We report an unusual constellation of diseases in a 32-year-old woman with neurofibromatosis type 1 (NF1) diagnosed with the recently described precursor entity of malignant peripheral nerve sheath tumor (MPNST), the so-called atypical neurofibromatous neoplasm with unknown biological potential (ANNUBP) and a large symptomatic cervical arteriovenous fistula. An [F] 2-Fluoro-2-deoxy-D-glucose PET/CT (FDG-PET/CT) was performed to detect and stage a conspicuous symptomatic cervical tumor. The FDG-PET/CT showed high FDG uptake in one of the multiple known tumorous lesions associated with peripheral nerves.

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: Nigeria is among the top five countries that have the highest gap between people reported as diagnosed and estimated to have developed tuberculosis (TB). To bridge this gap, there is a need for innovative approaches to identify geographical areas at high risk of TB transmission and targeted active case finding (ACF) interventions. Leveraging community-level data together with granular sociodemographic contextual information can unmask local hotspots that could be otherwise missed.

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One of the most important figures in the history of neurohistology, Giuseppe Levi (1872-1965) contributed in numerous ways to neuroscience, particularly in the fields of neuronal plasticity and the understanding of sensory ganglia. His daughter Natalia Ginzburg, Levi (1916-1991), on the other hand, achieved fame as one of the most celebrated Italian writers of the twentieth century. (), from 1963, is a semibiographical account of her life in which she describes the life and character of her father in detail, providing depth and complexity to a seminal figures in the development of neuroscience.

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Objective: Peripheral nerve tumors (PNTs) are rare diseases. So far, no multicenter data on diagnostics, the efficacy of treatment, long-term outcomes, and health-related quality of life (HRQoL) exist. The establishment of the Peripheral Nerve Tumor Registry (PNTR) in 2015 allows for the systematic analysis of patients with tumors associated with peripheral nerves.

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  • Charles Foix (1882-1927) is recognized for his contributions to vascular neurology and for syndromes bearing his name, but he also had a significant literary career.
  • His poetry and plays, often focusing on biblical and Greek mythological themes, were influenced by his experiences as a medical officer during the First World War in Greece.
  • The authors analyze how Foix's literary works relate to his medical career and the impact of his wartime experiences on his writing.
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  • - Synaptic dysfunction plays a crucial role in SHANK-associated disorders like autism, schizophrenia, and Phelan-McDermid syndrome, but understanding its effects on synaptic structure is limited.
  • - The study used advanced imaging techniques (expansion and STED microscopy) to examine the synaptic nanostructures in both human and mouse brain tissues, focusing on SHANK3-KO mice.
  • - Findings revealed unique shape profiles of murine postsynaptic scaffolds and significant changes in the organization of synaptic domains due to SHANK3 deficiency, shedding light on the molecular mechanisms of synaptic dysfunction in neuropsychiatric disorders.
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This longitudinal study aimed to analyze the evolution of patterns of daily activities (physical activity time, screen usage time, and sleep hours) in European youth during school closure due to the COVID-19 health crisis. Participants were 624 caregivers of children and adolescents aged 3-18 from Italy, Spain, and Portugal. Evaluations were online, and four time-points were considered: retrospective measurement of daily activities before confinement (T1), and two (T2), five (T3), and eight (T4) weeks after starting the lockdown.

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Atopic dermatitis (AD) has become a global health concern due to an increase in its frequency over the past few decades. This illness not only reduces the quality of life but also imposes a considerable financial burden due to the increased risk of skin infections. This case report explores the presentation of a four-month-old male infant with a personal history of atopic dermatitis that developed yellow scaly lesions on the scalp, which were assumed to be cradle cap.

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Supracondylar humerus fractures are the most common elbow fractures in children up to 10 years of age. The incidence of associated nerve injuries varies up to 15% depending on the data. Traumatic and iatrogenic lesions mainly affect the ulnar nerve.

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Tumorous or tumour-like lesions of peripheral nerves are generally rare, heterogeneous and challenging to diagnose and treat. They may become apparent by a palpable swelling (lump) near nerves, sensory and/or motor deficits, pain to touch or neuropathic pain. In 91% of cases, tumours are benign.

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Brachial plexus reconstruction (BPR) consists of the complex surgical restoration of nerve structures. To further understand the underlying motor cortex changes and evaluate neuroplasticity after a successful surgery, we performed a navigated transcranial magnetic stimulation (nTMS) study mapping the postoperative motor representation of the formerly plegic arm. We conducted a prospective nTMS study mapping the musculocutaneous nerve as a representative, prominent target of BPR including a patient ( = 8) and a control group ( = 10).

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Introduction: A supracondylar process is a bony spur on the distal anteromedial surface of the humerus, and it is considered an anatomical variant with a prevalence of 0.4-2.7% according to anatomical studies.

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Background: Neurogenic Thoracic Outlet Syndrome (nTOS) describes a complex of symptoms caused by the compression of neural structures at the upper thoracic outlet. Typical symptoms include pain, numbness and motor weakness of the affected extremity. The incidence of nTOS is 2-3 per 100,000 and is highest between the ages of 25 and 40.

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Article Synopsis
  • * A study analyzed pre-, intra-, and postoperative data from 22 patients, primarily affecting nerves in the upper extremities, with various surgical interventions employed based on intraoperative findings.
  • * At a 10-month follow-up, most patients reported significant improvements in motor function, with clinical assessments showing increased muscle strength after surgical intervention.
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