Publications by authors named "Pedro M Juiz-Gonzalez"
Article Synopsis
- The study examines how social restrictions and different variants, specifically Alpha, Delta, and Omicron-BA.1, affected the spread of SARS-CoV-2 in Galicia, Spain.
- Using genomic data and mobility statistics, the research found that initial variant introductions mostly came from other Spanish regions and France, later shifting to include imports from Portugal and the U.S.
- Despite the number of introductions, most did not contribute significantly to the pandemic's evolution in Galicia, but major coastal cities were identified as key areas for viral transmission.
Article Synopsis
- The study investigates how social restrictions and different variants, specifically Alpha, Delta, and Omicron, affected SARS-CoV-2 transmission in Galicia, Spain.
- Using genomic data and mobility information, the research shows that the Alpha variant initially spread from other Spanish regions and France, while later variants saw increased influences from Portugal and the USA.
- Key coastal cities in Galicia were identified as significant hubs for the virus's dissemination, underscoring the importance of regional connectivity for public health strategies.
Temporal progression of the distribution of Streptococcus pneumoniae serotypes causing invasive pneumococcal disease in Galicia (Spain) and its relationship with resistance to antibiotics (period 2011-2021).
Isabel Losada-Castillo Isolina Santiago-Pérez Pedro Miguel Juiz-Gonzalez Susana Méndez-Lage María Jesús Purriños-Hermida
Enferm Infecc Microbiol Clin (Engl Ed)
April 2024
Introduction: Streptococcus pneumoniae causes serious diseases in the susceptible population. The 13-valent pneumococci conjugate vaccine (PCV13) was included in the children's calendar in 2011. The objective of the study was to analyze the evolution of pneumococcal serotypes and their resistance after PCV13.
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- A severely immunosuppressed 28-year-old man with HIV-1 and COVID-19 had a prolonged SARS-CoV-2 infection lasting 15 weeks, marked by a unique Alpha variant with a specific mutation.
- Despite a robust T-cell immune response against the virus, the individual exhibited signs of immunological exhaustion, which may have contributed to the sustained infection.
- No significant intra-host evolution of the virus was observed during the prolonged infection, indicating that the virus remained relatively stable despite the prolonged presence in the host.
Objective: To evaluate clinical and antibiotic resistance impact of carbapenems stewardship programs.
Methods: descriptive study, pre-post-intervention, between January 2012 and December 2019; 350-bed teaching hospital. Prospective audit and feedback to prescribers was carried out between January 2015 and December 2019.