Publications by authors named "Pedro Lucas Negromonte Guerra"
Epidemiological and clinical characteristics of primary spinal cord glioblastomas: A systematic review and meta-analysis.
Pedro Lucas Negromonte Guerra Inaê Carolline Silveira da Silva Deoclides Lima Bezerra Júnior Anderson Albert Primo Lopes Geraldo de Sá Carneiro Filho
J Clin Neurosci
December 2024
Article Synopsis
- Primary spinal cord glioblastomas (GBMs) are rare but aggressive tumors that primarily affect young males, exhibiting distinct clinical characteristics compared to cranial GBMs.
- A systematic review analyzed data from 237 patients, revealing that most tumors occur in the cervical and thoracic spine, with motor deficits as the main symptom.
- Patients typically underwent surgery, with many receiving additional chemotherapy and radiotherapy; the average progression-free survival was 11.5 months and overall survival was 15.3 months, showing no significant differences based on sex or age.
Primary melanocytic tumors originating from CNS melanocytes are rare, with a low incidence of 0.7 cases per 10 million annually. This study focuses on primary leptomeningeal melanocytomas, emphasizing their epidemiology, clinical characteristics, and diagnostic challenges.
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