Publications by authors named "Pedro J Miranda"
In this work, we study the mythological network of Odyssey of Homer. We use ordinary statistical quantifiers in order to classify the network as real or fictional. We also introduce an analysis of communities which allows us to see how network properties shall emerge.
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- The study introduces a new method called theoretical knock-out (KO) to redefine and compute biological importance using complex network models and random walks.
- The method involves calculating a flux vector from a directed graph to evaluate the influence of biological agents represented by network vertices.
- It allows researchers to determine the relative importance of these agents over time, facilitating predictions in various biological phenomena based on their roles and interconnections.
The phenomenon of oral tolerance refers to a local and systemic state of tolerance induced in the gut after its exposure to innocuous antigens. Recent findings have shown the interrelationship between cellular and molecular components of oral tolerance, but its representation through a network of interactions has not been investigated. Our work aims at identifying the causal relationship of each element in an oral tolerance network, and also to propose a phenomenological model that's capable of predicting the stochastic behavior of this network when under manipulation.
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