Publications by authors named "Pedro Henrique Siedschlag Schmidt"
Article Synopsis
- The review analyzed the effectiveness and safety of fezolinetant in treating moderate-to-severe vasomotor symptoms (VMS) in postmenopausal women, using data from several major medical databases.
- Five randomized controlled trials involving 3,302 patients showed that fezolinetant significantly reduced the frequency and severity of VMS, as well as improved quality of life and sleep for participants compared to a placebo.
- No significant differences in adverse events were found between the fezolinetant and placebo groups, indicating that it is a safe treatment option for managing menopause-related symptoms.
Endoscopic Third Ventriculostomy versus Ventriculoperitoneal Shunt in Patients with Obstructive Hydrocephalus: An Updated Systematic Review and Meta-Analysis.
Asian J Neurosurg
September 2023
Endoscopic third ventriculostomy (ETV) and ventriculoperitoneal shunt (VPS) are surgical methods for treating obstructive hydrocephalus. However, there is still disagreement regarding the most effective technique, in terms of both operative success and postoperative complications. Therefore, we performed a systematic review and meta-analysis to compare the efficacy and safety of these two methods in patients with obstructive hydrocephalus.
View Article and Find Full Text PDFPurpose: Conflicting evidence exists on the choice of surgical or non-surgical treatment of flail chest injuries. We aimed to perform a meta-analysis comparing outcomes in patients presenting flail chest undergoing surgical or non-surgical treatment.
Methods: Embase, PubMed, and Cochrane databases were searched for randomized controlled trials (RCTs) comparing surgery to no surgery in patients with acute unstable chest wall injuries.