Publications by authors named "Pedro Henrique Dala Nora Quatrin"
Correction: Large Clostridial Toxins: A Brief Review and Insights into Antigen Design for Veterinary Vaccine Development.
Rafael Rodrigues Rodrigues Mariliana Luiza Ferreira Alves Miguel Andrade Bilhalva Frederico Schmitt Kremer Clóvis Moreira Junior Pedro Henrique Dala Nora Quatrin
Mol Biotechnol
December 2024
Article Synopsis
- * Traditional vaccines for these toxins face challenges in production and effectiveness, prompting interest in recombinant vaccines and the need for better understanding of lesser-studied toxins.
- * The study highlights the potential of immunoinformatics to map immunodominant regions of these toxins, guiding future research to develop more effective vaccination strategies against severe animal infections.
Introduction: Chickens with Necrotic Enteritis (NE), caused by Clostridium perfringens, exhibit acute and chronic symptoms that are difficult to diagnose, leading to significant economic losses. Vaccination is the best method for controlling and preventing NE. However, only two vaccines based on the CPA and NetB toxins have been commercialized, offering partial protection, highlighting the urgent need for more effective vaccines.
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