Publications by authors named "Pedro Guilherme Coroa Dos Santos Silva"
Article Synopsis
- - The study analyzed the effectiveness of the DCV/SOF treatment regimen for hepatitis C virus (HCV) in Brazilian patients, revealing a high sustained virologic response (SVR) rate of 95.4% among 132 patients, including those coinfected with HIV.
- - It found that drug resistance-associated substitutions (RASs) in the NS5A gene were more prevalent in HCV/HIV co-infected patients (28%) compared to monoinfected patients (16.8%), while differences in the NS5B gene were not significant between the groups.
- - The genetic analysis showed that a significant number of baseline mutations were present, particularly in genotype 1b strains, but these mutations generally did
