Publications by authors named "Pedro Galindo-Bonilla"

Introduction: Sugammadex is a cyclodextrin that reverses neuromuscular blockade, especially of rocuronium. The occurrence of anaphylaxis produced by its use is of 1:1000 and 1:20000; it is observed mainly in subjects of Asian origin.

Case Report: A 9-year-old boy of Asian origin who, after the administration of sugammadex, immediately manifested an episode of anaphylaxis, which was reverted by using adrenaline and antihistamines.

View Article and Find Full Text PDF
Article Synopsis
  • The study focused on identifying factors that contribute to the failure of asthma treatment step-down in patients with moderate to severe asthma who were on a combination therapy of inhaled glucocorticoids and long-acting beta agonists.
  • Results showed that 41.7% of patients experienced step-down failure, with significant factors including older age, multiple comorbidities, severity of asthma, and a short duration of previous asthma control.
  • The conclusion emphasizes that successful step-down is more likely when patients have maintained asthma control for over 6 months, suggesting that careful consideration is needed before adjusting treatment.
View Article and Find Full Text PDF

Background: β-Lactam antibiotics are the most common trigger of reactions in children with most of them being nonimmediate (85.5%), but proven allergy after the allergological workup is between 7% and 10%. There is no agreement on how to perform the provocation tests in these types of hypersensitivity reactions.

View Article and Find Full Text PDF

Objective: The aim of the present study was to analyze the influence of dissociation on the "false allergy" phenomenon.

Method: Fifty-five individuals (11 males and 44 females) who consecutively presented for the study of their suspected drug allergy were assessed.

Results: After the challenge test, false allergy was found in 39.

View Article and Find Full Text PDF