Functionally Graded Materials and Structures: Unified Approach by Optimal Design, Metal Additive Manufacturing, and Image-Based Characterization.

Functionally Graded Materials (FGMs) can outperform their homogeneous counterparts. Advances in digitalization technologies, mainly additive manufacturing, have enabled the synthesis of materials with tailored properties and functionalities. Joining dissimilar metals to attain compositional grading is a relatively unexplored research area and holds great promise for engineering applications.

Bioresorbable scaffolds for bone tissue engineering: optimal design, fabrication, mechanical testing and scale-size effects analysis.

Bone scaffolds for tissue regeneration require an optimal trade-off between biological and mechanical criteria. Optimal designs may be obtained using topology optimization (homogenization approach) and prototypes produced using additive manufacturing techniques. However, the process from design to manufacture remains a research challenge and will be a requirement of FDA design controls to engineering scaffolds.