Publications by authors named "Pedro Ferreira"

Introduction: Rib resection and remodeling have gained attention as cosmetic procedures to enhance body contours, particularly waist-to-hip ratio. Historically, rib resection has been used for medical reasons; however, plastic surgeons have recently adopted it for aesthetic purposes. However, concerns remain regarding the safety and effectiveness of the procedure, particularly due to the potential for complications, such as pneumothorax, chronic pain, and impaired respiratory function.

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In the flower development study, we identified SCI1 (Stigma/style Cell-cycle Inhibitor 1), a regulator of cell proliferation. SCI1 interacts with NtCDKG;2 ( Cyclin-Dependent Kinase G;2), a homolog of human CDK11, which is responsible for RanGTP-dependent microtubule stabilization, regulating spindle assembly rate. In a Y2H screening of a cDNA library using NtCDKG;2 as bait, a RanBP1 (Ran-Binding Protein 1) was revealed as its interaction partner.

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Land use change threatens global biodiversity and compromises ecosystem functions, including pollination and food production. Reduced taxonomic α-diversity is often reported under land use change, yet the impacts could be different at larger spatial scales (i.e.

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Introduction And Objectives: International guidelines for the diagnosis of Hypersensitivity Pneumonitis (HP) have improved the diagnostic standardization of this heterogeneous interstitial lung disease. Our goal was to determine how the final multidisciplinary discussion confidence level for suspected fibrotic HP (fHP) can be impacted by the application of different guidelines validated in this context.

Materials And Methods: Retrospective study including patients submitted to transbronchial lung cryobiopsy (TBLC) with a final multidisciplinary meeting diagnosis of fHP.

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Background: Mozambique is one of the countries with the highest prevalence of schistosomiasis, although there is little data on the prevalence of disease and associated morbidity in the adult population. This study aimed to describe and characterize the morbidity associated with schistosomiasis in the adult population of Chókwè district and to explore the use of anamnestic questionnaires and urine dipsticks, as well as point-of-care ultrasound for urinary related findings, to better characterize disease prevalence and morbidity.

Methodology: Between April and October 2018, we conducted a cross-sectional study embedded within the Chókwè Health Research and Training Centre.

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Microglia are crucial for brain development and their function can be impacted by postnatal insults, such as early-life allergies. These are characterized by an upregulation of interleukin (IL)-4 levels. Allergies share a strong comorbidity with Autism Spectrum Disorders (ASD) and Attention-Deficit/Hyperactivity Disorder (ADHD).

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  • Intravoxel incoherent motion (IVIM) imaging traditionally has low sensitivity in measuring heart perfusion, prompting the development of a more effective stimulated-echo (STEAM) method for better assessment of cardiac microstructure and perfusion.
  • The new STEAM-IVIM technique collects data at 20 different b-values and 6 diffusion directions, allowing thorough analysis of heart tissue in 20 healthy individuals.
  • The results indicate high-quality imaging with promising IVIM parameters and diffusion tensor metrics, suggesting that this method can detect abnormalities in heart microstructure and perfusion without needing contrast agents.
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  • - The HHH Workshop held in Dubrovnik in July 2023 focused on advancing the understanding of the Higgs boson and its properties within the Standard Model (SM).
  • - To confirm or challenge the SM, researchers need to measure the full potential of the Higgs, including the triple and quartic scalar couplings, particularly involving three scalar bosons at around 125 GeV.
  • - The report highlights ongoing experimental efforts and theoretical models aimed at improving measurement rates and addressing challenges related to multi-scalar final states.
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Pollen dispersal by insects determines the patterns of reproductive encounters between plants with flowers that have spatially or temporally segregated sexes. Pollinators exhibit varied responses to environmental gradients, such as those in grassland-forest ecotones. Individual-based interaction networks are useful yet underexplored tools to understand how interactions vary across these gradients.

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Summary: APAtizer is a tool designed to analyze alternative polyadenylation events on RNA-sequencing data. The tool handles different file formats, including BAM, htseq, and DaPars bedGraph files. It provides a user-friendly interface that allows users to generate informative visualizations, including Volcano plots, heatmaps, and gene lists.

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Resting tremor (RT) is a Parkinson's disease (PD) symptom with an unclear relationship to the dopaminergic system. We analysed data from 432 subjects from the Parkinson's Progression Markers Initiative, 57 additional PD patients and controls and 86 subjects referred for dopamine transporter single-photon emission computed tomography (DaT-SPECT). Caudate binding ratio (CBR), but not putamen binding ratio, was higher in RT patients.

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Photobiomodulation (PBM) shows beneficial effects on obesity-related alterations. It is not known if dual- is more beneficial than single-wavelength, nor the dose-response effect of such treatments. The effects of different doses of single- and dual-wavelength whole-body PBM on metabolic parameters in obese mice were evaluated.

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Background: Malaria is a devasting parasitic disease that causes over half a million deaths every year. The necessity for prompt and thorough antimalarial drug discovery and development is accelerated by the rise in multidrug resistance and the lack of an effective vaccine. The spp.

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Immune-mediated necrotizing myopathy (IMNM) is a rare form of inflammatory myopathy characterized by severe muscle weakness, elevated serum creatine kinase (CK) levels, and myofiber necrosis with minimal inflammatory infiltrates. IMNM is frequently associated with autoantibodies, particularly anti-3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR), and is often linked to statin use. However, it can also develop in statin-naïve patients, especially following viral infections.

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Thanks to recent developments in cardiovascular magnetic resonance (CMR), cardiac diffusion-weighted magnetic resonance is fast emerging in a range of clinical applications. Cardiac diffusion-weighted imaging (cDWI) and diffusion tensor imaging (cDTI) now enable investigators and clinicians to assess and quantify the tridimensional microstructure of the heart. Free-contrast DWI is uniquely sensitized to the presence and displacement of water molecules within the myocardial tissue, including the intracellular, extracellular, and intravascular spaces.

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Background And Aims: Microstructural disturbances underlie dysfunctional contraction and adverse left ventricular (LV) remodelling after ST-elevation myocardial infarction (STEMI). Biphasic diffusion tensor cardiovascular magnetic resonance (DT-CMR) quantifies dynamic reorientation of sheetlets (E2A) from diastole to systole during myocardial thickening, and markers of tissue integrity [mean diffusivity (MD) and fractional anisotropy (FA)]. This study investigated whether microstructural alterations identified by biphasic DT-CMR: (i) enable contrast-free detection of acute myocardial infarction (MI); (ii) associate with severity of myocardial injury and contractile dysfunction; and (iii) predict adverse LV remodelling.

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  • The study investigates the stability of Rest Tremor (RT) as a symptom in Parkinson's Disease (PD) and its connection to brain circuits and disease mechanisms over five years of data from the PPMI cohort.
  • It was found that RT is more stable than traditional Tremor-Dominant classifications, especially in terms of therapy responses, suggesting RT may represent a distinct subtype of PD.
  • Patients with therapy-resistant RT showed a unique profile with fewer gastrointestinal issues and lower rates of certain sleep disorders, indicating different disease progression patterns compared to those who respond to treatment or do not experience tremors.
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The sugarcane weevil (Sphenophorus levis Vaurie, 1978) is currently considered the most important sugarcane pest in Brazil, causing significant yield losses. Application methods of insecticides for S. levis control have not been effective, mostly due to the insect's cryptic behavior below the soil surface which suppresses the correct placement of insecticide active ingredients on target.

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  • - Acute Coronary Syndrome (ACS) involves symptoms or confirmation of acute ischemia or myocardial infarction, primarily indicated by ST segment elevation (STE), but many cases don’t fit typical STEMI criteria.
  • - A case study illustrates a 50-year-old man with anginal pain and an unusual EKG pattern (Aslanger's pattern) that indicated severe blockage in the left anterior descending artery and chronic right coronary artery occlusion.
  • - The distinction between STEMI and NSTEMI can be misleading, as one-third of NSTEMI patients may have complete coronary blockage; recognizing various EKG patterns, including Aslanger's, is vital for better diagnosis and treatment of ACS.
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  • - The SCI1 gene in Nicotiana tabacum plays a crucial role in plant reproductive organ size by regulating cell proliferation and interacting with proteins involved in the cell cycle.
  • - Researchers identified the interaction between SCI1, a cyclin-dependent kinase (NtCDKG;2), and a newly discovered RNA helicase (NtRH35) through various experimental methods, revealing their association in subcellular structures like splicing speckles.
  • - This study highlights SCI1 and its interactors as novel components of the spliceosome, suggesting that SCI1 may influence cell proliferation via splicing processes, which enhances our understanding of plant developmental pathways.
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Plants thrive in diverse environments, where root-microbe interactions play a pivotal role. Date palm (Phoenix dactylifera L.), with its genetic diversity and resilience, is an ideal model for studying microbial adaptation to different genotypes and stresses.

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Fire plays a key role in grasslands, determining the distribution and evolution of species and boundaries with neighboring ecosystems. Evidence of community-wide responses to fire is largely based on taxonomic and functional descriptors, while the phylogenetic dimension is overlooked. Here we evaluated how the taxonomic and phylogenetic structure of grassland plant communities responded to a time since fire (TSF) gradient.

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Neotropical fishes exhibit remarkable karyotype diversity, whose evolution is poorly understood. Here, we studied genetic differences in 60 individuals, from 11 localities of one species, the wolf fish Hoplias malabaricus, from populations that include six different "karyomorphs". These differ in Y-X chromosome differentiation, and, in several cases, by fusions with autosomes that have resulted in multiple sex chromosomes.

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