Publications by authors named "Pedro Celiny R- Garcia"
Objectives: To describe pulmonary resistance in children undergoing invasive mechanical ventilation (MV) for different causes.
Design: A cross-sectional study.
Setting: Two PICUs in the South region of Brazil.
Brazilian Translation, Cross-Cultural Adaptation, Validity, and Reliability of the EMpowerment of PArents in THe Intensive Care 30 (EMPATHIC-30) Questionnaire to Measure Parental Satisfaction in PICUs.
Pediatr Crit Care Med
June 2021
Article Synopsis
- The study aimed to translate, adapt culturally, validate, and test the reliability of the EMPATHIC-30 questionnaire for Brazilian parents of children discharged from the PICU.
- The translation followed best practices, resulting in a total content validity coefficient above the accepted average, indicating strong content relevance.
- Reliability testing showed varying results across different domains, with the overall internal consistency being excellent at 0.90, confirming the instrument's reliability for future use in assessing parental empowerment in intensive care settings.
Article Synopsis
- - This study aimed to assess serum ferritin levels measured within 48 hours of hospital admission as a predictor of mortality in pediatric sepsis patients, highlighting a significant link between ferritin levels and adverse outcomes.
- - Conducted at a tertiary care hospital in South America, it included 350 children aged 6 months to 18 years diagnosed with sepsis, identifying a 40.3% prevalence of iron deficiency anemia among them.
- - Findings revealed that higher serum ferritin levels correlated with increased mortality rates, with a notable 10-fold increase in ferritin associated with five times the risk of mortality, indicating that ferritin can be a valuable prognostic marker in this setting.
Objective: To verify the association between prone position, increased diuresis, and decreased cumulative fluid balance in critically ill pediatric patients who underwent mechanical ventilation (MV) for pulmonary causes and describe adverse events related to the use of the position.
Methods: This is a retrospective observational study. Patients aged between 1 month and 12 years who underwent MV for pulmonary causes, between January 2013 and December 2015, were selected and divided between those who were put on prone position (PG) and those who were not (CG) during the hospitalization at the Pediatric Intensive Care Unit (PICU).
Prevalence, mortality and risk factors associated with very low birth weight preterm infants: an analysis of 33 years.
J Pediatr (Rio J)
October 2020
Objective: To assess the prevalence, mortality and risk factors associated with the birth of very low birth weight preterm infants over a period of 33 years.
Methods: Four cross-sectional studies were analyzed, using data from perinatal interviews of birth cohorts in the city of Pelotas collected in 1982, 1993, 2004, and 2015. Based on perinatal questionnaires, anthropometric measurements of newborns and death certificates were analyzed to obtain the prevalence rate, neonatal mortality, and risk factors (maternal age, income and type of delivery) for very low birth weight.
Objective: The aim of this study was to present a review on the evolution, development, and consolidation of the pediatric emergency abroad and in Brazil, as well as to discuss the residency program in this key area for pediatricians.
Data Sources: This was a narrative review, in which the authors used pre-selected documents utilized as the minimum requirements for the Residency Program in Pediatric Emergency Medicine and articles selected by interest for the theme development, at the SciELO and Medline databases, between 2000 and 2017.
Data Synthesis: The historical antecedents and the initial evolution of pediatric emergency in Brazil, as well as several challenges were described, regarding the organization, the size, the training of professionals, and also the regulation of the professional practice in this new specialty.
Article Synopsis
- The study aimed to explore how echocardiogram results, ferritin levels, C-reactive protein, and leukocyte counts relate to poor outcomes in pediatric sepsis patients.
- A prospective cohort study included children aged 28 days to 18 years who had sepsis and required prolonged mechanical ventilation and vasoactive drugs; key indicators were measured over 72 hours.
- Results showed that higher ferritin levels and signs of cardiac dysfunction were linked to longer hospital stays, more extended mechanical ventilation, and a higher inotropic agent usage, indicating worse health outcomes for the patients.
Objectives: To evaluate the mechanism of insulin modulation on somatotrophic response, inflammation, and lipid metabolism in critically ill children.
Design: Open-label randomized mechanistic study.
Setting: Two-center, tertiary PICU study.
Sepsis: From the Stone Age to Nowadays Without a Precise Definition.
Pediatr Crit Care Med
August 2016
Article Synopsis
- The study aimed to review how nutritional status affects critically-ill pediatric patients in intensive care, focusing on their hospital stay duration, mechanical ventilation needs, and mortality rates.
- A review of seven articles published between 1982 and 2012 showed that poor nutritional status at admission correlated with worse patient outcomes, although the studies varied in quality and methods.
- The findings suggest that nutritional depletion negatively impacts pediatric patient outcomes, highlighting the need for more contemporary and consistent research in this area.
The aim of this study was to evaluate the medical and nursing care provided to children in the last 24 hours of life in two Brazilian paediatric intensive care units and analyse the nurses' participation in the decision-making process for life support limitation (LSL). The study was based on an analysis of the patients' medical charts, looking at the medical and nursing care provided in the last 24 hours of life during a 6-month period in the two units, and on semi-structured interviews with 20 nurses to evaluate their participation in LSL decisions. The children were classified into two groups: those who were to receive full cardiopulmonary resuscitation (CPR) and a non-CPR group.
View Article and Find Full Text PDFObjective: To evaluate demographic characteristics, mechanical-ventilation parameters, blood gas values, and ventilatory indexes as predictors of extubation failure in infants with severe acute bronchiolitis.
Methods: We conducted a prospective observational study from March 2004 to September 2005 with consecutive infants (ages 1-12 months) with severe acute bronchiolitis and considered ready to be extubated. We calculated mean airway pressure and oxygenation index.
Article Synopsis
- The study aimed to validate the PELOD score in pediatric intensive care units in South America using data from over 1,400 admissions.
- The results indicated that while the PELOD score showed excellent discrimination in predicting mortality, it struggled with calibration, overestimating mortality rates in certain risk intervals.
- Researchers caution against using the PELOD score as a definitive measure in clinical trials due to its issues with calibration, despite its reproducibility and strong predictive capacity.
Objective: To describe the characteristics of children submitted to prolonged mechanical ventilation (MV), and evaluate their mortality, and associated factors as well as the potential impact at admissions to the pediatric intensive care unit (PICU).
Methods: We conducted a retrospective study enrolling all children admitted to three Brazilian PICUs between January 2003 and December 2005 submitted to MV > or =21 days. The three selected PICUs were located in university-affiliated hospitals.
Objectives: To evaluate the hemodynamic responses to nociceptive stimuli in children submitted to videolaparoscopic appendectomy under balanced anesthesia with isoflurane and dexmedetomidine.
Methods: Randomized, double-blind and placebo-controlled study involving 26 children submitted to videolaparoscopic appendectomy carried out at Hospital São Lucas (PUCRS) between May 2004 and February 2005. Patients were assigned to two groups: (a) Dexmedetomidine group (n=13): infusion of 1 microg/kg over 10 minutes and maintenance dose of 0.
Current perspectives for treating children with diabetic ketoacidosis.
J Pediatr (Rio J)
November 2007
Objective: To review current concepts of physiopathology, diagnosis and treatment of diabetic ketoacidosis (DKA) in childhood, as well as preventive measures to avoid cerebral edema.
Sources: The authors selected articles from MEDLINE with the keywords diabetes, ketoacidosis, hyperglycemia and cerebral edema, and priority was given to studies including children and that contained complete texts published in English, Portuguese or Spanish. Chapters of books published in Brazil describing the treatment of DKA in pediatric intensive care unit were also reviewed.
Objectives: Septic shock (SS) is a frequent cause for admission to the pediatric intensive care unit, requiring prompt recognition and intervention to improve outcome. Our aim is to review the relevant literature related to the diagnosis and management of SS and present a sequential management for its treatment.
Sources: Non-systematic review of medical literature using the MEDLINE database.
Objective: To study the relationship between serum glucose level and mortality in children with septic shock.
Design: Prospective cohort study.
Setting: Twelve-bed pediatric intensive care unit at the Hospital São Lucas da PUCRS, Porto Alegre, Brazil.