Comparative analysis of clinical, biochemical and genetic aspects associated with bone mineral density in small for gestational age children.

Clinical, biochemical and genetic analysis related to bone mineral density (BMD) were carried out in children born small for gestational age (SGA) that failed to achieve postnatal catch-up growth (CUG), SGA children that completed CUG and adequate for gestational age (AGA) children. Serum IGF-I, IGF-II, IGF binding protein-3 and acid-labile subunit were lower in the SGA-CUG children as compared with the other groups. Frequencies of polymorphic variants of vitamin D receptor, estrogen receptor and collagen genes were similar among groups.

Surgical treatment of late-onset post-traumatic partial seizures in a child.

Introduction: Although post-traumatic epilepsy accounts for a small number of epileptic patients, it should not be underestimated since it primarily affects children and young adults and can result in psychosocial disability and death.

Case Report: We present the case of a 14-year-old girl referred to us because of refractory partial seizures. The patient had experienced a head trauma at the age of 6 months requiring surgical treatment due to a large right fronto-temporo-parietal extradural hematoma.