Publications by authors named "Pedro Amorim-Machado"
Article Synopsis
- CD4(+) regulatory T cells (Tregs) help maintain immune balance by regulating T cell activation, which is crucial for preventing autoimmune responses.
- Research on 53 HIV-infected patients undergoing highly active antiretroviral therapy (HAART) showed that those with low CD4(+) T cell counts (Nadir <200 cells/µL) and high Tregs percentages had poorer immune recovery.
- The study indicates that a high frequency of Tregs can negatively impact CD4(+) T cell recovery, particularly in individuals who don’t respond well to treatment, suggesting that monitoring Tregs levels could be important for optimizing HAART strategies.
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