Measuring Streptococcus mutans, Streptococcus sanguinis and Candida albicans biofilm formation using a real-time impedance-based system.

Candida albicans and streptococci are amongst the most common fungal and bacterial organisms present in the oral cavity, with a growing body of evidence implicating C. albicans in increased caries severity and in the formation of the cariogenic biofilm. However, the interactive mechanisms between cariogenic streptococci and Candida are yet to be elucidated.

K21 Compound, a Potent Antifungal Agent: Implications for the Treatment of Fluconazole-Resistant HIV-Associated Species.

With mucocutaneous candidiasis being highly prevalent in HIV patients, the emergence of fluconazole-resistant species forms a major challenge in treating and eradicating these infections. The objective of this study was to establish the antifungal activity of K21, a membrane-rupturing antimicrobial compound derived from a silica quaternary ammonium compound (SiQAC) with tetraethoxysilane (TEOS). The study sample included 81 species of which 9 were type strains and 72 were clinical isolates.

antifungal drug resistance in sub-Saharan African populations: A systematic review.

: infections are responsible for increased morbidity and mortality rates in at-risk patients, especially in developing countries where there is limited access to antifungal drugs and a high burden of HIV co-infection.  This study aimed to identify antifungal drug resistance patterns within the subcontinent of Africa.  : A literature search was conducted on published studies that employed antifungal susceptibility testing on clinical isolates from sub-Saharan African countries using Pubmed and Google Scholar.