Publications by authors named "Pedro A Esteves-Guerreiro"
Article Synopsis
- Sleep-related issues are common in early-onset epileptic encephalopathies and developmental delays, especially in autism spectrum disorders, but the genetic connections are not well understood.
- A gene enrichment study identified common risk genes and pathways between sleep disturbances and rare genetic syndromes, showing notable overlaps in genes related to synaptic functions.
- The findings suggest that specific molecular mechanisms linked to circadian rhythm disruptions might underlie both sleep problems and neurodevelopmental disorders, paving the way for future research into these shared biological factors.
