Publications by authors named "Pedram Parva"
Deep learning and transfer learning for brain tumor detection and classification.
Biol Methods Protoc
November 2024
Article Synopsis
- Convolutional neural networks (CNNs) are advanced tools for image classification that mimic biological vision systems and allow for transfer learning, enabling them to adapt knowledge from one task to another.
- This study examines the effectiveness of using CNNs for brain cancer detection by incorporating a unique transfer learning step from camouflage animal detection, enhancing the models' ability to recognize tumors in MRI scans.
- Results indicated that these networks not only accurately identified brain tumors but also considered surrounding tissue changes, demonstrating a level of performance comparable to trained radiologists.
Perivascular spaces (PVS) visible on brain MRI signal cerebral small vessel disease (CSVD). The coexistence of PVS with other CSVD manifestations likely increases the risk of adverse neurological outcomes. We related PVS to other CSVD manifestations and brain volumes that are markers of vascular brain injury and neurodegeneration.
View Article and Find Full Text PDFPerivascular space (PVS) burden is an emerging, poorly understood, magnetic resonance imaging marker of cerebral small vessel disease, a leading cause of stroke and dementia. Genome-wide association studies in up to 40,095 participants (18 population-based cohorts, 66.3 ± 8.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates the prevalence of Enlarged Perivascular Spaces (ePVS), linked to Cerebral Small Vessel Disease (CSVD), across different ages and sexes in a large community sample.
- Findings show that ePVS prevalence rises with age for both men and women, correlating with an increased presence of vascular risk factors like hypertension and smoking.
- The results suggest that ePVS could serve as a useful biomarker for age-related brain vascular issues, indicating a connection between vascular health and cognitive decline.
Objective: Enlarged perivascular spaces have emerged as markers of cerebral small vessel disease and are linked to perivascular drainage dysfunction. The apolipoprotein E-ɛ4 (APOE-ɛ4) allele is the strongest genetic risk factor for cerebral amyloid angiopathy and Alzheimer's neuropathology, but the underlying mechanisms remain unclear. We studied the relationship between APOE-ɛ4 and the topography and burden of enlarged perivascular spaces to elucidate underlying mechanisms between APOE-ɛ4 and adverse clinical outcomes.
View Article and Find Full Text PDFObjective: To describe the prevalence, severity, and location of ankle injuries as assessed on magnetic resonance imaging (MRI) in athletes participating in the Rio de Janeiro 2016 Summer Olympic Games.
Methods: We analyzed all ankle MRIs that were acquired for suspected injury as reported by the National Olympic Committee medical teams and the Organizing Committee medical staff during the Rio 2016 Summer Olympics. Diagnostic imaging was performed through the Olympic Village Polyclinic.
Proliferative myositis (PM) along with proliferative fasciitis and nodular fasciitis are a group of pseudosarcomatous myofibroblastic proliferations. Although the histologic presentation of each is almost identical, the magnetic resonance imaging (MRI) appearance of proliferative myositis is closer to that of inflammatory myopathies. We report a case of PM in which the imaging and histologic features combine typical findings of PM with unusual imaging features, suggesting of reactive (or nodular) fasciitis.
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