Publications by authors named "Pedram M"

This study developed an animal model with internal and external urethral sphincter insufficiency by bypassing the sphincter without major damage so that the animal under study can return to normal life after the study. There is a need for a reliable, applicable, and reproducible animal model for studying urinary incontinency disease due to incorrect sphincter function. Seven adult male dogs were used for this study.

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A new Iranian population of is characterized, including morphometrics, microphotographs, and molecular (18S, 28S rDNA) studies. It is compared with previously known populations. The results derived from molecular analyses failed to find close evolutionary relationships with other traditional genera of Belondiridae and Swangeriinae, adding more uncertainties about the internal phylogeny of the family.

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The potassium sodium-activated channel subtype T member 1 () gene encodes the Slack channel K1.1, which is expressed in neurons throughout the brain. Gain-of-function variants in are associated with a spectrum of epilepsy syndromes, and mice carrying those variants exhibit a robust phenotype similar to that observed in patients.

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Dealing with spinal cord injuries presents problematic due to multiple secondary mechanisms. Beyond primary concerns like paralysis and disability, complications including urinary, gastrointestinal, cardiac, and respiratory disorders, along with substantial economic burdens may occur. Limited research focuses on modeling and treating contusion and compression injuries.

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Root-knot nematodes (RKNs) are the most destructive nematode species in main pistachio cultivation areas of Iran, and adversely affect crop quality and yield. So far, and have been reported infecting pistachio. In this study, four populations of were found infecting pistachio in Kerman and Khorasan Razavi provinces.

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Using integrated pest management without relying on chemical pesticides is one of the most attractive approaches to controlling plant pathogens. Among them, using resistant cultivars or rootstocks against diseases in combination with beneficial microorganisms has attracted special attention. The citrus nematode is one of the major constraints of citrus cultivation worldwide.

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The considerable amount of energy utilized by buildings has led to various environmental challenges that adversely impact human existence. Predicting buildings' energy usage is commonly acknowledged as encouraging energy efficiency and enabling well-informed decision-making, ultimately leading to decreased energy consumption. Implementing eco-friendly architectural designs is paramount in mitigating energy consumption, particularly in recently constructed structures.

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Four species of the genus were recovered from southern (Bushehr province) and southeastern (Southern Khorasan province) Iran. The first species, n. sp.

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n. sp. was recovered from rotten wood samples of an unidentified forest tree in the Mazandaran province and described herein.

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Two new species of the genus found in northern Iran are characterized, including morphological descriptions and molecular (18S-, 28S-rDNA) analyses. sp. nov.

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Background: Coronary microvascular dysfunction is prevalent in women with signs and symptoms of ischemia but no obstructive coronary artery disease (CAD) and is associated with an adverse prognosis. Elevated pericardial fat volume predicts adverse cardiac events, but mechanistic pathways of the association are not well understood.

Methods: 118 women enrolled in the NHLBI-sponsored Women's Ischemia Syndrome Evaluation-Coronary Vascular Dysfunction study with suspected coronary microvascular dysfunction but no obstructive CAD underwent adenosine stress 1.

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Unlabelled: Neuronal activity stimulates mRNA translation crucial for learning and development. While FMRP (Fragile X Mental Retardation Protein) and CYFIP1 (Cytoplasmic FMR1 Interacting Protein 1) regulate translation, the mechanism linking translation to neuronal activity is not understood. We now find that translation is stimulated when FMRP and CYFIP1 translocate to the potassium channel Slack (KCNT1, Slo2.

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Background: Robotic spinal surgery may result in better pedicle screw placement accuracy, and reduction in radiation exposure and length of stay, compared to freehand surgery. The purpose of this randomized controlled trial (RCT) is to compare screw placement accuracy of robot-assisted surgery with integrated 3D computer-assisted navigation versus freehand surgery with 2D fluoroscopy for arthrodesis of the thoraco-lumbar spine.

Methods: This is a single-centre evaluator-blinded RCT with a 1:1 allocation ratio.

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Article Synopsis
  • The study investigates the use of human placental mesenchymal stem cell-derived exosomes (HPMSCs-Exosomes) to treat severe spinal cord injuries (SCI) in rats, focusing on improvements in motor function.
  • Researchers conducted intrathecal injections of these exosomes during the acute phase of SCI and observed significant functional recovery over a six-week period compared to control groups.
  • Results indicate that HPMSCs-Exosomes reduce neuron apoptosis, lower glial scar formation, and promote tissue preservation, suggesting a promising therapeutic strategy for enhancing recovery after SCI.
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In this article, we introduce GEMA, a genome exact mapping accelerator based on learned indexes, specifically designed for FPGA implementation. GEMA utilizes a machine learning (ML) algorithm to precisely locate the exact position of read sequences within the original sequence. To enhance the accuracy of the trained ML model, we incorporate data augmentation and data-distribution-aware partitioning techniques.

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Smoking is the leading cause of preventable death worldwide. Cigarette smoke includes thousands of chemicals that are harmful and cause tobacco-related diseases. To date, the causality between human exposure to specific compounds and the harmful effects is unknown.

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Activation of specific brain areas and synchrony between them has a major role in process of emotions. Nevertheless, impact of anti-synchrony (negative links) in this process still requires to be understood. In this study, we hypothesized that quantity and topology of negative links could influence a network stability by changing of quality of its triadic associations.

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Objective: To investigate hemodynamics and morphology of hip joint vasculature in cats with the use of color and pulsed-wave Doppler ultrasonography.

Animals: 30 client-owned healthy skeletally immature cats presented for routine examinations between September 7, 2022, and March 25, 2023.

Methods: Cats between 3.

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The skin undergoes the formation of fine lines and wrinkles through the aging process; also, burns, trauma, and other similar circumstances give rise to various forms of skin ulcers. Induced pluripotent stem cells (iPSCs) have become promising candidates for skin healing and rejuvenation due to not stimulating inflammatory responses, low probability of immune rejection, high metabolic activity, good large-scale production capacity and potentials for personalized medicine. iPSCs can secrete microvesicles (MVs) containing RNA and proteins responsible for the normal repairing process of the skin.

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During a nematological survey in southern Iran, a population belonging to the family Tylenchidae was recovered from a tomato field in Bushehr province. The recovered population belongs to the genus was described and illustrated herein as n. sp.

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Researchers have been leveraging wearable cameras to both visually confirm and automatically detect individuals' eating habits. However, energy-intensive tasks such as continuously collecting and storing RGB images in memory, or running algorithms in real-time to automate detection of eating, greatly impacts battery life. Since eating moments are spread sparsely throughout the day, battery life can be mitigated by recording and processing data only when there is a high likelihood of eating.

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A new species from the family Tylenchidae was recovered in the grasslands of Isfahan province, Iran, and is herein described based on morphological and molecular data. n. sp.

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