Publications by authors named "Pediredla Karunakar"
Aim: Undernurition stands as a significant contributor to childhood mortality, particularly in developing nations such as India. At the grass root level, anthropometric monitoring indicators such as stunting, underweight and wasting take place within Anganwadi centres (village courtyard). The scrutiny of growth records, utilising these markers, not only quantifies the burden but also informs corrective measures.
View Article and Find Full Text PDFA rare case of congenital insensitivity to pain with anhidrosis.
Paediatr Int Child Health
August 2024
A 22-month-old girl of consanguineous parents was admitted with a high-grade fever. She was found to have insensitivity to painful stimuli and an absence of perspiration. She also displayed self-mutilating behaviour and was insensitive to cold/hot water on her body.
View Article and Find Full Text PDFObjective: Significant involvement of the cardiovascular system is known in multisystem inflammatory syndrome in children (MIS-C). This study aimed to examine the recovery of affected cardiovascular parameters over a medium-term follow-up.
Methods: A cohort of 69 children was studied prospectively.
Article Synopsis
- Leukocyte adhesion deficiency (LAD) is a disorder that affects neutrophil function, leading to difficulty in leukocytes sticking to blood vessel walls, which results in recurrent infections, particularly from bacteria like Staphylococcus aureus and Pseudomonas aeruginosa.
- A specific condition discussed is ecthyma gangrenosum (EG), which presents as a painful skin ulcer with a black center and red halo, often linked to severe bacterial infections.
- The case report highlights an atypical instance of LAD type-1 presenting with extensive EG in the perineum, caused by Staphylococcus hominis, and successfully treated using a combination of granulocyte transfusion and a diversion col
Information on the genetic profile of congenital nephrotic syndrome (CNS) from India is scarce. The management of CNS is largely supportive of the setting of developing countries, mainly via the administration of intravenous albumin infusions, angiotensin-converting enzyme inhibitors, and levothyroxine. Inadequate infrastructure and management facilities, including genetic analyses, further hamper the outcome.
View Article and Find Full Text PDFObjective: To study the clinico-etiological spectrum and outcomes of children with rapidly progressive glomerulonephritis (RPGN).
Methods: This retrospective cohort study evaluated patients <18 years with RPGN, over an 8-year period (2014-2022), for etiology and kidney outcomes.
Results: Among 68 RPGN cases [median age 10 (7,12) years], 23 (33.
Background: There is paucity of information regarding the etiology and outcomes of Acute Kidney Disease (AKD) in children.
Methods: The objectives of this cohort study were to evaluate the etiology and outcomes of AKD; and analyze predictors of kidney survival (defined as free of CKD 2, 3a, 3b, 4 or 5). Patients aged 1 month to 18 years who developed AKD over a 4-year-period (January 2018-December 2021) were enrolled.
Clinical profile and outcomes of multisystem inflammatory syndrome in children (MIS-C): Hospital-based prospective observational study from a tertiary care hospital in South India.
J Paediatr Child Health
November 2022
Aim: To study the clinical profile and outcomes in children with multisystem inflammatory syndrome in children (MIS-C).
Methods: Children aged 1 month to 15 years presenting with MIS-C (May 2020 to November 2021) were enrolled. Clinical, laboratory, echocardiography parameters and outcomes were analysed.
A 7-month-old male infant was referred to us for evaluation of hypercalcemia and failure to thrive. He was the second-born child to third-degree consanguineous parents with a birth weight of 3.5 kg.
View Article and Find Full Text PDFBackground: There is a paucity of data from India on ophthalmological complications in children on long-term oral corticosteroids for idiopathic nephrotic syndrome.
Methods: All children aged 4-18 years with idiopathic nephrotic syndrome who had received long-term oral steroids for >6 months and who attended the paediatric nephrology clinic between January 2019 and January 2021 were included. The majority of them (95/110) were being followed up in the paediatric nephrology clinic which was functioning from 2010.