Supplementation of docosahexaenoic acid (DHA), vitamin D and uridine in combination with six weeks of cognitive and motor training in prepubescent children: a pilot study.

Background: Learning and memory have been shown to be influenced by combination of dietary supplements and exercise in animal models, but there is little available evidence from human subjects. The aim of this pilot study was to investigate the effect of combining a motor- and cognitive exercise program with dietary supplementation consisting of 500 mg docosahexaenoic acid (DHA), 10 μg vitamin D and 1000 mg uridine (DDU-supplement) in 16 prepubescent children (age 8-11 years).

Methods: We designed a randomized, placebo-controlled, double-blinded study lasting 6 weeks in which DDU-supplement or placebo was ingested daily.

Individualized, home-based interactive training of cerebral palsy children delivered through the Internet.

Background: The available health resources limit the amount of therapy that may be offered to children with cerebral palsy and the amount of training in each session may be insufficient to drive the neuroplastic changes, which are necessary for functional improvements to take place. The aim of this pilot study was to provide proof of concept that individualized and supervised interactive home-based training delivered through the internet may provide an efficient way of maintaining intensive training of children with cerebral palsy over prolonged periods.

Methods: 9 children (aged 9-13 years) with cerebral palsy were included in the study.