Posterior Mediastinal Mass: An Uncommon Presentation of a Branchial Cleft Cyst.

Branchial cleft anomalies are a heterogeneous group of congenital disorders that theoretically emerge due to incomplete obliteration of the branchial apparatus, components of the six main pairs of pharyngeal arches, during embryonic development. They can result in a cyst, a sinus, or a fistula. For a congenital lateral neck mass, they represent the most common diagnosis in pediatric neck pathology.

Release of Nanoparticles in the Environment and Catalytic Converters Ageing.

A Three-Way Catalyst (TWC) contains a cordierite ceramic monolith coated with a layer of AlO, CeZrO and platinoids mixture. Under standard operation, the platinoid concentration decreases, exposing the remaining washcoat structure. After that particle release stage, the sintering process follows where the crystalline CeZrO solution is broken and begins to separate into ZrO and CeO phases.

Oncolytic adenovirus with hyaluronidase activity that evades neutralizing antibodies: VCN-11.

Tumor targeting and intratumoral virus spreading are key features for successful oncolytic virotherapy. VCN-11 is a novel oncolytic adenovirus, genetically modified to express hyaluronidase (PH20) and display an albumin-binding domain (ABD) on the hexon. ABD allows the virus to self-coat with albumin when entering the bloodstream and evade neutralizing antibodies (NAbs).

Perimetric progression using the Visual Field Index and the Advanced Glaucoma Intervention Study score and its clinical correlations.

Purpose: To evaluate the association between clinical parameters and the diagnosis of progression using VFI (Visual Field Index) and AGIS (Advanced Glaucoma Intervention Study) score in primary open angle glaucoma.

Methods: Retrospective study of 517 visual fields of 78 eyes with primary open angle glaucoma analyzed with VFI and AGIS score. Clinical data registered included: age, sphere, pachimetry, basal intraocular pressure (IOP), and IOP during the follow up.

Increased learning and brain long-term potentiation in aged mice lacking DNA polymerase μ.

A definitive consequence of the aging process is the progressive deterioration of higher cognitive functions. Defects in DNA repair mechanisms mostly result in accelerated aging and reduced brain function. DNA polymerase µ is a novel accessory partner for the non-homologous end-joining DNA repair pathway for double-strand breaks, and its deficiency causes reduced DNA repair.

[Choroidal folds. A presentation of two cases].

Clinical Case: We report two patients of 29 and 50 years old presenting with unilateral choroidal folds in posterior segment in which, after a complete ophthalmic examination, we suspected an acquired hyperopic shift syndrome. Fluorescein angiography and magnetic resonance imaging revealed a flattening of posterior globes and distended perineural subarachnoid spaces.

Discussion: Acquired hyperopia with choroidal folds is a benign condition characterised by the acute development of a unilateral or bilateral hyperopic shift in refractive error.

Intraoperative mitomycin C and corneal endothelium after pterygium surgery.

Purpose: To determine the effect of mitomycin C (MMC) on the corneal endothelium after primary pterygium surgery.

Methods: This prospective, interventional, nonrandomized, observer-masked study included 46 consecutive patients (51 eyes) with primary pterygium. The bare sclera technique with 1-minute application of 0.

[Alterations in nocturnal melatonin secretion in patients with optic neuropathies].

Objective: To study nocturnal melatonin suppression induced by exposure to light in patients with bilateral optic neuropathies.

Methods: Observational, prospective case control study. Twenty patients were included in this study and distributed in 3 groups: Group A (n=5, Healthy Control Subjects), Group B (n=10, Experimental Patients) and Group C (n=5, Blind Control Subjects).

Optical absorption, TL and IRSL of basic plagioclase megacrysts from the pinacate (Sonora, Mexico) quaternary alkalic volcanics.

The paper presents the first results of an investigation on optical absorption (OA), thermally and infrared stimulated luminescence (TL and IRSL) of the Pinacate plagioclase (labradorite). The OA spectra reveal two bands with maxima at 1.0 and 3.