Antifungal Activity against of 2,6-Dimethoxy-4-(phenylimino)cyclohexa-2,5-dienone Derivatives.

In this work the enzyme laccase from was used to synthetize 2,6-dimethoxy-4-(phenylimino)cyclohexa-2,5-dienone derivatives. Ten products with different substitutions in the aromatic ring were synthetized and characterized using ¹H- and C-NMR and mass spectrometry. The 3,5-dichlorinated compound showed highest antifungal activity against the phytopathogen , while the -methoxylated compound had the lowest activity; however, the antifungal activity of the products was higher than the activity of the substrates of the reactions.