Nano-modified screen-printed electrode-based electrochemical immunosensors for oral cancer biomarker detection in undiluted human serum and saliva samples.

This proposed work reports the development of in-house made conductive ink-based screen-printed electrodes (SPEs) for label-free detection of oral cancer biomarkers. Carbon ink synthesis includes graphite powder, gum arabic, and water. The selectivity test of the fabricated SPE involves immobilizing antibodies specific to biomarkers and challenges with redox-active interference, other serum molecules, and non-target biomarkers.

Fabrication of alkoxysilane substituted polymer-modified disposable biosensing platform: Towards sperm protein 17 sensing as a new cancer biomarker.

SP17 is a mammalian protein found in the testis and spermatozoa that have been identified as a tumor-associated antigen in a range of human cancers. A unique method for fabricating the first ultrasensitive, selective, and label-free immunosensor for the detection of SP17, a new cancer biomarker in complicated serum samples, is presented in this paper. This immunosensor was also the first biosensor built using a disposable ITO sheet modified with an aminosilane known as APTMS as an immobilization platform for fabricating the SP17 biosensor.

Simple and facile carbon dots based electrochemical biosensor for TNF-α targeting in cancer patient's sample.

Tumour Necrosis Factor (TNF-α) is a pro-inflammatory cytokine having key roles in cell death, differentiation, survival, proliferation, migration and is a modulator of immune system. Therefore, TNF-α is an ideal biomarker for several disease diagnosis including cancer. However, out of all the biomarkers of cancer, TNF-α) is less explored for cancer detection.

Impact of Covid19 on electricity load in Haryana (India).

As it is known that the whole world is battling against the Corona Virus Disease or COVID19 and trying their level best to stop the spread of this pandemic. To avoid the spread, several countries like China, Italy, Spain, America took strict measures like nationwide lockdown or by cordoning off the areas that were suspected of having risks of community spread. Taking cues from the foreign counterparts, the government of India undertook an important decision of nationwide full lockdown on March 25th which was further extended till May 4th, 2020 (47 days-full lockdown).

COVID-19 pandemic lockdown: An emotional health perspective of Indians on Twitter.

Background: Novel corona virus (2019-nCoV) has spread in the world since its first human infection in December 2019. India has also witnessed a rising number of infections since March 2020. The Indian government imposed lockdowns in the nation to control the movement of its citizens thereby confining the spread of the virus.

Single-wall carbon nanotube based electrochemical immunoassay for leukemia detection.

A label-free electrochemical immunosensor is fabricated using high quality single-walled carbon nanotube for early detection of leukemia cells. It is based on P-glycoprotein (P-gp) expression level detection; by effective surface immune-complex formation with the monoclonal anti-P-glycoprotein antibodies bound to an epoxy modified nanotube surface. The expression level of P-gp on the leukemia cell surface detected by cyclic voltammetry is in good agreement with immunofluorescence microscopy studies.