Publications by authors named "Pawel Treichel"
Article Synopsis
- Pediatric patients with primary refractory or relapsed B-cell non-Hodgkin lymphoma (B-NHL) have a poor prognosis, as indicated by a study of 76 patients treated in Poland from 1995 to 2022.
- The 5-year overall survival probability was 76.7% and event-free survival probability was 72.9%, but outcomes worsened for those with disease progression or relapse, particularly with a 0.0% survival rate for relapsing patients.
- Key factors affecting prognosis included elevated lactate dehydrogenase, presence of B symptoms, and advanced disease at diagnosis, with hematopoietic stem cell transplantation showing potential as the most effective salvage therapy.
Oral findings such as inflammation, ulcerations, or lesions can indicate serious systemic diseases and should prompt suspicion of acquired chronic conditions or inborn errors of immunity (IEIs). Currently, there are approximately 500 disease entities classified as IEIs, with the list expanding annually. The awareness of the existence of such conditions is of paramount importance, as patients with these disorders frequently necessitate the utilization of enhanced diagnostic techniques.
View Article and Find Full Text PDFArticle Synopsis
- The study focuses on pediatric patients under 18 with non-B non-Hodgkin lymphomas (NHL), particularly rare types, examining their outcomes at a single oncology center over 20 years.
- Out of 26 children analyzed, 14 had anaplastic large cell lymphoma (ALCL), 9 had T-cell lymphoblastic lymphoma (TLL), and 3 had rare NHL types, with overall survival rates showing promising results comparable to clinical trials.
- The conclusion highlights the need for more research and dedicated clinical trials on rare NHLs to develop better treatment guidelines and strategies.
An organism's ability to function properly depends not solely on its diet but also on the intake of nutrients and non-nutritive bioactive compounds that exert immunomodulatory effects. This principle applies both to healthy individuals and, in particular, to those with concomitant chronic conditions, such as type 2 diabetes. However, the current food industry and the widespread use of highly processed foods often lead to nutritional deficiencies.
View Article and Find Full Text PDF