Background: N-terminal pro-brain natriuretic peptide (NT-proBNP) release is associated with left ventricular expansion and pressure overload. Elevation of serum levels of natriuretic peptides is observed in patients with impaired as well as preserved left ventricular systolic function. High NT-proBNP has been shown to be related not only to preload but also to increased afterload, especially blood pressure and arterial stiffness.
View Article and Find Full Text PDFBACKGROUND Advanced heart failure (HF) is commonly accompanied by central sleep apnea (CSA) with Cheyne-Stokes respiration (CSR). The aim of this study was to evaluate the relationship between CSA/CSR and other clinical features of HF, with particular emphasis on cardiovascular hemodynamics. MATERIAL AND METHODS In 161 stable HF patients with left ventricular ejection fraction (LVEF) ≤45% (NYHA class I-III; mean LVEF 32.
View Article and Find Full Text PDFUnlabelled: Left ventricular diastolic dysfunction (LVDdf) and arterial stiffness are associated with increased mortality in patients with arterial hypertension.
The Aim: of the study was to evaluate the relation between left ventricular diastolic function and hemodynamic profile assessed by impedance cardiography (ICG).
Material And Methods: In 209 hypertensives clinical evaluation, echocardiography and ICG were performed to evaluate i.
Correlation of the thickness of the left ventricular posterior wall (LVPWd) with various parameters, including age, gender, weight and height, was investigated in this study using regression models. Multicenter derived database comprised over 4,000 healthy individuals. The developed models were further utilized in the in vitro-in vivo (IVIV) translation of the drug cardiac safety data with use of the mathematical model of human cardiomyocytes operating at the virtual healthy population level.
View Article and Find Full Text PDFBackground: Short periods of cerebral ischaemia during ventricular defibrillation testing may be associated with neuropsychological impairment. However, the impact of out-of-hospital ventricular fibrillation (VF) converted by implantable cardioverter-defibrillator (ICD) shock on cognitive functioning is unknown.
Aim: To assess the impact of out-of-hospital VF converted by ICD shock on cognitive functioning.
Background: Exercise oscillatory ventilation (EOV) is a common pattern of breathing in heart failure (HF) patients, and indicates a poor prognosis.
Aim: To investigate the effects of adaptive servoventilation (ASV) on ventilatory response during exercise.
Methods: We studied 39 HF patients with left ventricular ejection fraction (LVEF) £ 45.
Background: The evaluation of the left ventricular (LV) function is one of the most important elements of diagnosis in patients with cardiovascular (CV) diseases. A low LV ejection fraction (LVEF) is a strong and independent predictor of CV events. Traditionally, echocardiography characterises the LV systolic function by the estimation of LVEF with use of the Simpson method, supported by the wall motion score index (WMSI).
View Article and Find Full Text PDFOne can seldom meet heart as a place of the cardiac tumors process in reference to both primary and metastatic changes. While taking transthoracic echocardiography one ought to remember of possibility of cardiac tumour in this particular place. In this case report presenting four cases of the cardiac tumors authors underline that this type of tumor can be found in each cardiac chamber.
View Article and Find Full Text PDFCytotoxicity of drugs can be a cause of cardiorespiratory disorders connected with chemotherapy. Doxorubicin is an antibiotic from the group of anthracyclines effective in antineoplastic therapy of solid and hematopoetic tumors. The most common cause of therapy ceasing is its cardiotoxicity.
View Article and Find Full Text PDFBackground: Microvolt T-wave alternans (MTWA) is a promising method for noninvasive assessment of arrhythmic risk. Recent studies have shown good immediate reproducibility of T-wave alternans. Little is known about it during the long term.
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