The In Vitro Ability of to Form Biofilm and the Potential of Various Compounds to Eradicate It from Urinary Catheters.

Urinary infections related to the presence of bacterial biofilm on catheters are responsible for loss of patients' health and, due to their high frequency of occurrence, generate a significant economic burden for hospitals. is a pathogen frequently isolated from this type of infection. In this study, using a cohesive set of techniques performed under stationary and flow conditions, we assessed the ability of 120 strains to form biofilm on various surfaces, including catheters, and evaluated the usefulness of clinically applied and experimental compounds to remove biofilm.

Efficacy and safety of kaolin-based hemostatic pad vs. standard mechanical compression following transradial and transulnar access for elective coronary angiography and PCI: RAUL trial substudy.

Hemostatic devices used in the transradial approach (TRA) and transulnar approach (TUA) are limited. This study compared the efficacy and safety of hemostasis using the QuikClot Radial hemostatic pad (QC) vs. standard mechanical compression (SC) after coronary angiography (CAG).

A high precision gas flow cell for performing in situ neutron studies of local atomic structure in catalytic materials.

Gas-solid interfaces enable a multitude of industrial processes, including heterogeneous catalysis; however, there are few methods available for studying the structure of this interface under operating conditions. Here, we present a new sample environment for interrogating materials under gas-flow conditions using time-of-flight neutron scattering under both constant and pulse probe gas flow. Outlined are descriptions of the gas flow cell and a commissioning example using the adsorption of N by Ca-exchanged zeolite-X (NaCaAlSiO,x ≈ 38).

A new computational approach to the classification of fluoroquinolones according to the Biopharmaceutical Classification System.

Background: Two main factors, which have an influence on oral absorption from solid, immediate release dosage form, are solubility and permeability. These are considered the main fundamental properties that govern the rate and extent of oral absorption. The significance of these properties has been highlighted in the Biopharmaceutics Classification System (BCS).

How a Nanostructure's Shape Affects its Lifetime in the Environment: Comparing a Silver Nanocube to a Nanoparticle When Dispersed in Aqueous Media.

Herein, we detail how the morphology of a nanomaterial affects its environmental lifetime in aquatic ecosystems. In particular, we focus on the cube and particle nanostructures of Ag and age them in various aquatic mediums including synthetic hard water, pond water, and seawater. Our results show that in the synthetic hard water and pond water cases, there was little difference in the rate of morphological changes as determined by UV-vis spectroscopy.

[Natriuretic peptides and their use in clinical practice according to the guidelines of the European Society of Cardiology].

In recent years, assay levels of natriuretic peptides are used in everyday clinical practice. The most commonly used is the assay the concentration of NT-proBNP in conjunction with the longest half-life (120 minutes) and its stability. According to the guidelines of the European Society of Cardiology determination of NT-proBNP were used in the diagnosis of acute and chronic heart failure, risk stratification in acute coronary syndromes, pulmonary embolism and in assessing the overall risk of cardiovascular patients prior to surgery.

Preliminary experience in sentinel node and occult lesion localization (SNOLL) technique-One center study.

Aim: The aim of this study was to present one center experience in applying the SNOLL technique to patients with suspected occult breast lesions.

Background: In the last years, the widespread use of mammographic screening programs resulted in an increasing number of women with nonpalpable suspicious breast lesions requiring further examination. The new method called sentinel node and occult lesion localization (SNOLL) enables the intraoperative detection of nonpalpable breast tumors and sentinel node biopsy in one surgical procedure.

Potential application of fabricated sulfide-based scintillation materials for radiation detection.

In our laboratories, we have produced ZnS(Ag)/6Li sol-gel scintillation materials which produce an excellent light output with an alpha radiation (compared to commercial high temperature lithiated glass; KG-2 and a plastic scintillator; BC-400). However, when tested with a neutron radiation, the opacity of the ZnS(Ag)/6Li sol-gel scintillation materials, which were composed of a homogeneous micron-sized ZnS(Ag), prevented a clear neutron energy peak formation, thus making it difficult to set a threshold for neutron-gamma discrimination. In an effort to increase the transparency of the scintillation materials and to develop new technologies to fabricate sulfide-based scintillation materials for neutron detection, we turned to the methods of a chemical bath deposition (CBD) and a nano-particle synthesis for possible solutions.

[Ectopic pregnancy rupture--can it be prevented?].

Objectives: To determine risk factors for ectopic pregnancy (EP) rupture based on the patients history and preoperative tests.

Materials And Methods: The retrospective study consisted of 175 women operated on due to EP in the Department of Gynecology and Oncology of the Jagiellonian University between 2000-2008. Tubal rupture was diagnosed at the time of surgery.

Metastable tetragonal phase CdWO4 nanoparticles synthesized with a solvothermal method.

CdWO4 has only previously been reported in the monoclinic, or wolframite, phase. Here we report the first metastable, tetragonal or scheelite, CdWO4 nanopowder. The tetragonal CdWO4 was synthesized by a propylene glycol solvothermal method.

Synthesis and activity of phosphinic tripeptide inhibitors of cathepsin C.

Phosphinic tripeptide analogues Gly-Xaapsi[P(O)(OH)CH(2)]-Gly have been developed as inhibitors of cathepsin C (DPP I), a lysosomal, papain-like cysteine protease. The target compounds were synthesised by addition of methyl acrylate to the appropriate phosphinic acids followed by the N-terminus elongation using mixed anhydride procedure. The latter step has been demonstrated to be a suitable method for N-terminal extension of the phosphinic pseudopeptide analogues without requirement of hydroxyphosphinyl protection.

[Fibrosing mediastinitis].

Up to date aspects of fibrosing mediastinitis are discussed in the review. The most common changes in the organs of mediastinum have been described with regard to surgical possibilities of their treatment, particularly superior caval vein syndrome, strictures of bronchial tree and pulmonary vessels and changes of the esophagus. The approach to rich literature has been pointed out.

The value of immune modulating parameters in predicting the progression from peritonitis to septic shock.

Intra-abdominal infection is one of the major causes of septic shock and multiple organ failure. To date, what causes the disease's progression remains unclear and therefore the relevance of immune modulating therapies remains speculative. The primary outcome measure of this study was to investigate immune modulating mediators at the onset of peritonitis before the development of subsequent septic shock.