Genetic Polymorphisms of , , , and in Polish Patients with Thoracic Aortopathy.

Background: The pathogenesis of thoracic aortopathy is complex, and much evidence suggests the influence of genetic factors. Some genes with polymorphisms are widely considered critical factors in the initiation and development of aortic aneurysm. The aim of our study was to analyze the association of genetic polymorphisms of rs1799750 (c.

Polymorphism of Interleukin 1B May Modulate the Risk of Ischemic Stroke in Polish Patients.

: Inflammation plays a crucial role in the pathophysiology of ischemic stroke (IS). Interleukin-1B and interleukin-1 receptor antagonists are key factors in inflammatory processes. Aims: The aims of our study were to evaluate the relationship between genetic variation in interleukin-1B () rs1143627 and interleukin-1 receptor antagonist () variable-number-tandem-repeats (VNTR), and overall IS and subtype prevalence rates.