Evolution of Light-Sensitive Proteins in Optogenetic Approaches for Vision Restoration: A Comprehensive Review.

Retinal degenerations, such as age-related macular degeneration and retinitis pigmentosa, present significant challenges due to genetic heterogeneity, limited therapeutic options, and the progressive loss of photoreceptors in advanced stages. These challenges are compounded by difficulties in precisely targeting residual retinal neurons and ensuring the sustained efficacy of interventions. Optogenetics offers a novel approach to vision restoration by inducing light sensitivity in residual retinal neurons through gene delivery of light-sensitive opsins.

Improving Actuator Wearing Using Noise Filtering.

Actuator, mostly valve, wearing is an important factor of the overall industrial control system operational cost. Actuator operational wear strongly depends on its operation. Highly utilized elements have a tendency to degrade faster.

Digital Twins in the Practice of High-Energy Physics Experiments: A Gas System for the Multipurpose Detector.

The digital twins technology delivers a new degree of freedom into system implementation and maintenance practice. Using this approach, a technological system can be efficiently modeled and simulated. Furthermore, such a twin offline system can be efficiently used to investigate real system issues and improvement opportunities, e.

Control quality assessment using fractal persistence measures.

Control Performance Assessment (CPA) has great practical importance. Control quality significantly affects final production throughput, efficiency and environmental impact. There are many approaches starting from time-domain methods, through Minimum Variance, Gaussian and non-Gaussian statistics up to alternative wavelet, fractal or entropy measures.

Non-Gaussian and persistence measures for control loop quality assessment.

This paper presents review and comparison of alternative methodologies for control performance assessment. The approach uses nonlinear time series analysis, such as non-Gaussian statistics, fractal, crossover analysis, or entropy-based approaches. There is a presented practical rationale for the analysis.